DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and T22F7.1

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_497209.1	Gene:	T22F7.1 / 3564822	WormBaseID:	WBGene00020701	Length:	510	Species:	Caenorhabditis elegans

Alignment Length:	461	Identity:	115/461 - (24%)
Similarity:	184/461 - (39%)	Gaps:	70/461 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 AIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSM-----NAELNWVCNDAYKARI 123
            |..||.|.|  ||              |.|..:....:|...|.     .|||.
Worm    95 AFTAPAGDE--CT--------------ENCSFYTIQNEFNLTSKFFLVEPAELT----------- 132

  Fly   124 GQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQC----GFVGDFLTTYASNLVQFAIFRCISGL 184
             .|::|||:|:....|.|:.||.||...:|:   |    |.||. |.:.|.|.....:.|.|.|.
Worm   133 -TSIYFLGNLLIGQLFAVVADRFGRRPIIII---CLLLTGIVGS-LGSLAPNFPLLLVARFIQGS 192

  Fly   185 AATANYYLMFILVLEYLAPKLRNM-----AISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSAL 244
            ..|....:.::|..|.:..:.:::     .:|...|.||     :|| |||....||.....:||
Worm   193 CYTPLTTVNYVLSGESIPHRSQSLTSIFFGVSWVCGYCF-----LAP-LSVWFNTWRSLQLATAL 251

  Fly   245 LQLVVALFYF-VVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFE---AFRRNCIVKRKL 305
            ..::||:|.. .:.||..:.|.:.|.:   |..|.|.....:..|..:::   ...:...:....
Worm   252 PNILVAVFLMGTLPESVGYSIEKKNRK---AVQKWIKRNELLSCKKLNYDLDMIMEKTEKIATSS 313

  Fly   306 SNQPEQTAGIFDLLR----TPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLS-PFVVFSLFAV 365
            |..|:....||:::|    ...:.:..::..|.::||.:::..:|.....:|.| |.|.|....|
Worm   314 SPTPQNRLTIFEMIREILSDREITRRIIVETFLWILTFMTYCALSLTSTSVGNSDPLVSFLFSGV 378

  Fly   366 VVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISM 430
            |..|:.....:..:|..|:.|.||... ||.::......||.:     .:|.|...|..:...|.
Worm   379 VELPAYLFIPICLTRTKRRPTRFLCHF-TGSMALLTMYFLSND-----TSLHLIIWLVAKFCASC 437

  Fly   431 CYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCT 495
            ||.....:|:||.||..||..|..........:.|:|::..:.:....|..|:||.:.|..||.|
Worm   438 CYIFCFIYAAELFPTWCRSCCIGVCSTCCNIGAIVAPHIFLIDSAAPGAQFLVLAAVGLLCSGLT 502

  Fly   496 LMLPET 501
            ....||
Worm   503 WCQQET 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	115/461 (25%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	91/361 (25%)
T22F7.1	NP_497209.1	MFS_SLC22	101..505	CDD:340875	110/450 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160163066
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950