DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14857 and CarT

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_610052.1	Gene:	CarT / 35334	FlyBaseID:	FBgn0032879	Length:	674	Species:	Drosophila melanogaster

Alignment Length:	612	Identity:	163/612 - (26%)
Similarity:	270/612 - (44%)	Gaps:	88/612 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 DFDQILEKCGSAGRYQYLMI--------LLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENR 57
            |.|.:|...|..|:||.|::        :..|:.||       :|..:...| .:||....|.:.
  Fly    35 DLDDLLPTIGEFGKYQKLLVFGICLPACIPCGFCAF-------NQLFMADTPDDYWCRIPELLDL 92

  Fly    58 SFEEIAAIYAPFGKE--------ASC--------TRLDKIEGDRVTVSNETC--------QRWIY 98
            ..|:..::..|  ||        :.|        ..|:..|.|.:|......        |.|.|
  Fly    93 PLEQRKSLSIP--KELDNDELVYSKCYTYGVNWTQLLESGEEDDLTTMEPNASWPLIKCPQGWEY 155

  Fly    99 NYDFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGD 163
            |....:.|:..:.:.||:......||.:....|..:|.:.||:|.||.||..:..:.......|.
  Fly   156 NTSVVWSSIVIDFDLVCDQDIYPTIGLAALNTGGPVGVYLFGLLNDRGGRRLSYFVCLATLLAGS 220

  Fly   164 FLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGIC--FCLGALVAP 226
            .:|:.:.:...:|..|.|.||...|.|.:.||:.||.:....|:..   |:..|  :..|.::..
  Fly   221 LMTSLSKDFWTWAGSRVIVGLTIPAVYQIPFIISLELVGENYRSFV---TVMTCTFYTSGIMLLS 282

  Fly   227 WLSVLAGNW-RI-YLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKA 289
            .::.|..:| |: |:|  :|......|:.||:.||.:||:.|..:|.|:..|:.:|..||.|...
  Fly   283 GVTYLERDWVRLSYIT--SLPFYAYFLYMFVMPESPRWLLMRGRLEEALKILERMAKVNGREFPE 345

  Fly   290 A---DFEA-FRRNCI--VKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRN 348
            |   ..|| .||:.:  .|:|::|     .|:.||.||||:|..::|:..::......:..:|..
  Fly   346 AVHLKLEAQIRRDKLKKQKKKMAN-----VGLADLCRTPNMRLKTILITLSWFANETVYLGLSYY 405

  Fly   349 VEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKN 413
            ...:|.:.:|.|.|.|||..||...........||:....|:|:..| ::|.:.|.|..:...:.
  Fly   406 GPALGTNQYVSFFLSAVVELPSYLCCWYFMDTWGRRWPLSLSMILGG-VACVITVMLPDDAVDET 469

  Fly   414 VTL-LLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVS-------PYLI 470
            :.| |::.||     :|..:.:...||.||.||.||..||.|       :|::.       |::.
  Fly   470 LVLYLVSKAL-----LSASFLIIYPFAGELYPTQVRGIGIGA-------SSYIGGLGLIGIPFIT 522

  Fly   471 HLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWR--RHDD 533
            :||......|.:|:..|.:......|.||||.:.:||.|:.:||.|||.....  ||.|  :..:
  Fly   523 YLGKDNLKLPLVIMGFLSMLGGMTGLRLPETLHHRLPQTIEEGEEFGKNWQFK--DCCRCAQKPE 585

  Fly   534 DVSKEATEEVRLHQLNGQTKSETEAEV 560
            .:|:.|:.| .|..|.|.:.:.:|.|:
  Fly   586 ILSQPASYE-NLDVLAGSSTNASEVEL 611

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	143/548 (26%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	100/361 (28%)
CarT	NP_610052.1	2A0119	44..561	CDD:273328	143/548 (26%)
CarT	NP_610052.1	MFS	182..551	CDD:119392	106/391 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	86	1.000	Inparanoid score	I1789
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	4	4.060