Protein Alignment CG14857 and Slc22a30

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_795976.1
• Gene: Slc22a30 / 319800
• MGIID: 2442750
• Length: 552
• Species: Mus musculus
• Alignment Length: 599
• Identity: 142/599 - (23%)
• Similarity: 239/599 - (39%)
• Gaps: 113/599 - (18%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALEN--------- 56
            |.|.::|.:.||.||:|.|.|..:.::......|...:|....:|.|.|:...|:|
Mouse     1 MAFQELLNQVGSLGRFQILQISFVLFLVGLVVPHITMENFTAAIPNHRCWAPILDNDTASDNGSR 65

  Fly    57 -RSFEEIAAIYAPFGKEASCTRLDK-------------IEGDRVTVSNET------C-QRWIYNY 100
             .|.:::..|..|..   |..||||             :.|   |.||||      | ..|:|:.
Mouse    66 ILSQDDLLRISIPLD---SNLRLDKCRRFAQPQWHLLHLNG---TFSNETEPDTEPCVDGWVYDR 124

  Fly   101 DFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFL 165
            .....::..|.:.||.......:.:..|.:|..:|....|.|.||.||              .|:
Mouse   125 SNFLSTIVTEWDLVCESQALNSVAKFSFMIGLFIGAIICGHLSDRFGR--------------KFI 175

  Fly   166 TTYASNLVQFAI----------------FRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTL 214
            .|.|  |:||||                .|.::|::.........:|:||:.:||...|.  ..|
Mouse   176 LTCA--LLQFAITETCVAFAPSFFIYCLLRFLAGMSVEPISVNSHLLMLEWTSPKFLGMV--AVL 236

  Fly   215 GICFC-LGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFVV-----QESAQWLITRTNVEGAI 273
            ..|.. :|.::...|:.|...||     ...|.:.|.:|:|::     .|||:|||.....:..:
Mouse   237 TSCAASIGYMILAGLAFLFRIWR-----HLQLAMSVPIFFFLILTRWMSESARWLIVTNKPQKGL 296

  Fly   274 ARLKHIAHFNGME-----VKAADFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVF 333
            ..|:.:||.|||:     :.....||..:|.:...|..:.|.      ||..||.|||...::.|
Mouse   297 KELRKVAHMNGMKNSGNTLTMEVVEASMKNELEAAKRKSSPR------DLFHTPILRKRICVLSF 355

  Fly   334 TFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLS 398
            ...|.::|...:|.:::.:..:..::..|.:.:......|...:.:.:||:.|..:.|...|:..
Mouse   356 MRYLFTISIFGLSLHLQHLSTNIILLQFLSSALGILISVIGHFVLNHMGRRITQLVLMSLRGIFM 420

  Fly   399 CALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGAS 463
            .............:.:...||.||.     |:|..|::...:|||||.:|:.|:..:.:......
Mouse   421 LTAVFVPQEMQTLRIIMATLAAALS-----SLCMCVSNLHINELLPTTLRATGMGVIAMFGNSGL 480

  Fly   464 FVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCW 528
            |::|..:.|.|..|..|.:......:.......:||||.|:.||.::.|          :..| |
Mouse   481 FLAPLFMLLATYSANLPWIFYGGFSILYGFSVFLLPETKNQPLPDSIHD----------VGND-W 534

  Fly   529 RRHDDDVSKEATEE 542
            :.     |::|.||
Mouse   535 KE-----SRQAKEE 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	132/554 (24%)
Slc22a30	NP_795976.1	MFS_OAT	109..516	CDD:340932	98/440 (22%)