Protein Alignment CG14857 and Slc22a15

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 555
• Identity: 141/555 - (25%)
• Similarity: 234/555 - (42%)
• Gaps: 76/555 - (13%)

  Fly     1 MDFDQILEKCGSAGRYQ-YLMILLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENRSFEEIA 63
            |:.::..:..|..|.|| ||..||...:............:||..| .||...|.|.|:|....:
  Rat     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMAELLPNQSHSNQS 65

  Fly    64 AIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLF 128
            :     ||       .:..||.:..:|.:......::...|.|:.:|...:.|.:||.....|.|
  Rat    66 S-----GK-------GQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSFF 118

  Fly   129 FLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQ----FAIFRCISGLAATAN 189
            |.|..:|..:||.|.||.||.:..:    .||..|.|...|:....    ||:.|.:.|:.....
  Rat   119 FSGVFVGVISFGQLSDRFGRKKVYL----TGFALDILFAIANGFSPSYEFFAVTRFLVGMMNGGM 179

  Fly   190 YYLMFILVLEYLAPKLRNMAISGTL-GICFCLGALVAPWLSVLAGNWRIYLTCSALLQL---VVA 250
            ..:.|:|:.|.:....  .|::|:: |:.|.:|......|.....:||   |.:.|:.|   ||.
  Rat   180 SLVAFVLLNECVGAAY--WALAGSIGGLFFAVGIAQYALLGYFIRSWR---TLAILVNLQGTVVF 239

  Fly   251 LFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKL---------S 306
            |....:.||.:||.::..:..|...|..||               :||    |||         :
  Rat   240 LLSLFIPESPRWLYSQGRLSEAEEALYLIA---------------KRN----RKLKCTFSLTHPA 285

  Fly   307 NQPEQTAGIF-DLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPS 370
            |:..:..|.| ||.|...|...:|:::|.:.:.||.:..::.:...:|.|.:...:|..::..||
  Rat   286 NRSYRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPS 350

  Fly   371 G--FIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLA------FALPMRLG 427
            .  .|..:.|...|||.| ..|.||.|.|:|.:.:.|    .:|..|.:.|      .:|..:|.
  Rat   351 YPLCIYLINQRWFGRKRT-LAAFLCLGGLACLIVMFL----PEKKDTGVFAVVNSHSLSLLGKLT 410

  Fly   428 ISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTAS 492
            ||..:.:...:.|||.||.:|:.|:....:.:.....::|::..|.....:.|.::.....||:.
  Rat   411 ISAAFNIVYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATGLTSG 475

  Fly   493 GCTLMLPETNNRQLPITLADGEAFG---KGESMLS 524
            ..:|:||||.|..|..|.:|.:.:.   .||..||
  Rat   476 LLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALS 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	134/525 (26%)
		MFS	126..470	CDD:119392	95/369 (26%)
Slc22a15	NP_001101177.1	MFS	111..469	CDD:119392	97/390 (25%)
		MFS_1	111..450	CDD:284993	94/371 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347224
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940