Protein Alignment CG14857 and Slc22a22

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 574
• Identity: 128/574 - (22%)
• Similarity: 222/574 - (38%)
• Gaps: 103/574 - (17%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALE---------- 55
            |.||:||...|..||:|..||::|..::..:::|...:|....:|.|.|....|:
  Rat     1 MAFDEILHHVGDRGRFQIWMIVVLNILSMVSSLHDVIENFTAAIPAHHCSVNLLDTSRSEISMAM 65

  Fly    56 NRSFEEIAAIYAPFG---KEASCTRLD----KIEGDRVTVSNET------C-QRWIYNYDFGFRS 106
            |.:.|.:..:..|.|   |...|.|..    :.....::.||.|      | ..|.|::.....:
  Rat    66 NLTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDGWTYDHSVFTST 130

  Fly   107 MNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAV--------ILANQCGFVGD 163
            :..|.:.||:........|:....|..:.....|::.||.||...:        ||...|.||.:
  Rat   131 IVTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMYCSLAYGILGTCCAFVPN 195

  Fly   164 FLTTYASNLVQFAIFRCISGLAATANYYLMFILVLE-----------YLAPKLRNMAISGTLGIC 217
            |..        :.:.|.:|..:|:.......|||||           .|:....:..::|..|:.
  Rat   196 FSL--------YCVLRFLSSASASTVGMNCLILVLEETSVQWHATVIVLSGLFSSTGLAGLGGLA 252

  Fly   218 FCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFV-------VQESAQWLITRTNVEGAIAR 275
            :.|            .:|.       |:||..||.||:       |.|||:||:.....:.|:..
  Rat   253 YVL------------SDWH-------LIQLTSALPYFIFFILFCWVPESARWLMITGKTDQALKE 298

  Fly   276 LKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSL 340
            |:.||..||.:..|.:.........||..:.:..:..: |.|::..|.:||:.|...........
  Rat   299 LQRIASINGKKDIAQNLTTEDLRSKVKEDVCSTVKHFS-IKDIIINPMIRKIVLCYSSVLFAELF 362

  Fly   341 SFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVAL 405
            |...:..:|..:|.:.||...|..|:..||..:...:...|.|:......:..||  .|.
  Rat   363 SIFGLLLDVHMLGKNIFVTQILLGVIDIPSKSLTYFILRNVRRRPLIAFLLFATG--GCI----- 420

  Fly   406 STEGAQKNVTLLLAFAL-PMRLGISM----CY----TVTSQFASELLPTCVRSRGIAAVHLAAAG 461
                   .:|:.|:..: .:||.|.:    |:    ::.:.:.:||.|..:||. :..::::.|.
  Rat   421 -------TITMFLSEDMYVLRLAIFILGKGCFAAFISINTAYCNELSPVPLRST-LNGIYISVAR 477

  Fly   462 -ASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGE 514
             ||.:|...:.........|.:...:|.:.|:.....||||.|..:..|:.|.|
  Rat   478 LASVLSALTLVTRKYFVLLPMIFCGVLPIVATINIYFLPETFNHPITDTIKDME 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	120/557 (22%)
		MFS	126..470	CDD:119392	82/379 (22%)
Slc22a22	NP_001013969.1	2A0119	11..526	CDD:273328	120/557 (22%)
		MFS	127..516	CDD:119392	89/431 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347417
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030