Protein Alignment CG14857 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 586
• Identity: 150/586 - (25%)
• Similarity: 246/586 - (41%)
• Gaps: 78/586 - (13%)

  Fly     1 MDFDQILEKCGSAGRYQ-YLMILLLGYIAFTTTVHYYSQNIIGFVP-QHWCYHEALENRSFEEIA 63
            |:.::..:..|..|.|| ||..||...:............:||..| .||...:.|.|:|...
Mouse     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSHSN-- 63

  Fly    64 AIYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLF 128
               ...||       .:..||.:..:|.:......::...|.|:.:|...:.|.:||.....|.|
Mouse    64 ---QTLGK-------GQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIANRSYKVSAASSSF 118

  Fly   129 FLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQ----FAIFRCISGLAATAN 189
            |.|..:|..:||.|.||.|| |.|.|.   ||..|.|...|:....    ||:.|.:.|:.....
Mouse   119 FSGVFVGVISFGQLSDRFGR-RKVYLT---GFALDILFAVANGFSPSYEFFAVTRFLVGMMNGGM 179

  Fly   190 YYLMFILVLEYLAPKLRNMAISGTL-GICFCLGALVAPWLSVLAGNWRIYLTCSALLQL---VVA 250
            ..:.|:|:.|.:....  .|::|:: |:.|.:|......|.....:||   |.:.|:.|   :|.
Mouse   180 SLVAFVLLNECVGTAY--WALAGSIGGLFFAVGIAQYALLGYFIRSWR---TLAVLVNLQGTLVF 239

  Fly   251 LFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKL---------S 306
            |....:.||.:||.::..:..|...|..||               :||    |||         :
Mouse   240 LLSLFIPESPRWLYSQGRLSEAEEALYFIA---------------KRN----RKLKCTFSLTHPA 285

  Fly   307 NQPEQTAGIF-DLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPS 370
            |:..:..|.| ||.|...|...:|:::|.:.:.||.:..::.:...:|.|.:...:|..::..||
Mouse   286 NRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPS 350

  Fly   371 G--FIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLA------FALPMRLG 427
            .  .|..:.|...|||.| ..|.||.|.|:|.:.:.|    .:|..|.:.|      .:|..:|.
Mouse   351 YPLCIYLINQRWFGRKRT-LAAFLCLGGLACLIVMFL----PEKKDTGVFAVVNSHSLSLLGKLT 410

  Fly   428 ISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTAS 492
            ||..:.:...:.|||.||.:|:.|:.|..:.:.....::|::..|.....:.|.::.....||:.
Mouse   411 ISAAFNIVYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGATGLTSG 475

  Fly   493 GCTLMLPETNNRQLPITLADGEAFG---KGESMLSFDCWRRHD--DDVSKEATEEVRLHQLNGQT 552
            ..:|:||||.|..|..|.:|.:.:.   .||..||........  |.||.|:.||...:..:.:|
Mouse   476 LLSLLLPETLNSPLLETFSDLQMYSYRRLGEEALSLQTLDPPQPLDKVSSESEEEEEFYDADEET 540

  Fly   553 K 553
            :
Mouse   541 Q 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	136/525 (26%)
Slc22a15	NP_001034460.2	MFS_SLC22A15	71..469	CDD:340935	109/430 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544		7/29 (24%)