Protein Alignment CG14857 and Slc22a22

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_036015188.1
• Gene: Slc22a22 / 210463
• MGIID: 2446114
• Length: 587
• Species: Mus musculus
• Alignment Length: 655
• Identity: 157/655 - (23%)
• Similarity: 253/655 - (38%)
• Gaps: 170/655 - (25%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRS------- 58
            ||||:||...|.:||:|..||:||..::...:.|...:|....:|.|.|......:||
Mouse     1 MDFDEILHHVGDSGRFQICMIILLNILSLVLSPHDVLENFTAAIPAHHCSINLDNSRSEVSTDMN 65

  Fly    59 --FEEIAAIYAPFG---KEASCTR--------LDKIEGDRVTVSNET------C-QRWIYNYDFG 103
              .|::..:..|.|   |...|.|        ||    ..::..|.|      | ..|.|::..
Mouse    66 LTTEDLMKVSIPMGPNQKPEQCRRFRYTQWQFLD----SNISTFNSTELETEPCLDGWTYDHSV- 125

  Fly   104 FRS------MNAELNW-------------VCNDAYKARI---------------GQSLFFLGSLM 134
            |.|      ::....|             .|.:..|:.:               .|:....|.|:
Mouse   126 FTSTIVTEGLSPPQPWDSDQYYHTKHEISPCEEGLKSSVKVWDLVCDFQSFKYYAQATSLAGHLV 190

  Fly   135 GTFTFGVLGDRIGRVRAVILANQC-GFVGDFLTTYASNLVQFAIFRCISGLAATANYYLM--FIL 196
            .....|::.||.||...::..:.. |.||.: ..:|.|...:.:.|.:  |:|..:..|:  .||
Mouse   191 SCPLSGIISDRFGRKPLLMYCSLAYGAVGTY-CAFAPNFSVYCVLRFL--LSAFQSTILINSLIL 252

  Fly   197 VLEYLA----PKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFYFV-- 255
            |||..:    |.:  :.:||...   .:|..|...|:.:..:|.       ||||..||.:|:
Mouse   253 VLEEASVQWHPTI--IVLSGLFN---SIGQGVLGGLAYVISDWH-------LLQLAYALPFFIFF 305

  Fly   256 -----VQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGI 315
                 |.||.:|||.....:.|...|:.||..||.:..|.:.....    ::.||......|..:
Mouse   306 VLFCWVPESVRWLIITGKTDQAWKELQRIASINGKKGIAQNLTTED----LRSKLKKDVNSTGKL 366

  Fly   316 F---DLLRTPNLRKV-----SLLVVFTFMLTSLSFNTISRNVEGMGLSPFV--VFSLFAVVVPPS 370
            |   |:...|.:||:     |||....|     ||..:..:|:.:|.:.|:  :| |.|:.||..
Mouse   367 FRIKDIFINPLIRKIVLSNSSLLFAELF-----SFVGLLLDVQLLGKNMFLTQIF-LGAIDVPSK 425

  Fly   371 GFIQGLLQSRVGRKATAFLAMLCTGLLSC-ALGVALSTEGAQKNVTLLLAFALPMRLGISMCYT- 433
            ......:::...|...||| :|.||  || .:.:.:|.|     :.:|......:..|....:|
Mouse   426 SLTYFTIRNVSRRPLIAFL-LLTTG--SCITITIFISEE-----MYVLRTIIFILGKGCFAAFTC 482

  Fly   434 VTSQFASELLPTCVRS--RGI--AAVHLAAAGASF---VSPYLIHLGTKLAAAPSLILALLLLTA 491
            :::.:.:||.|..:||  .|:  |.|.||...::.   ...|.::|       |.::..:|.:.|
Mouse   483 ISTTYINELSPVELRSTLNGVFLAVVRLAGVLSALTLATRKYFVYL-------PMILYGVLPIVA 540

  Fly   492 SGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSKEATEEVRLHQLN-----GQ 551
            :...|.||||.|  ||.|                        |:.|:..:..||...|     ||
Mouse   541 TISILFLPETFN--LPHT------------------------DIIKDMEKRKRLMSKNISKKEGQ 579

  Fly   552 TKSET 556
            ...||
Mouse   580 DFLET 584

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	141/591 (24%)
		MFS	126..470	CDD:119392	95/376 (25%)
Slc22a22	XP_036015188.1	MFS_OAT	108..548	CDD:340932	110/480 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167844057
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030