Protein Alignment CG14857 and Slc22a19

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_659034.1
• Gene: Slc22a19 / 207151
• MGIID: 2442751
• Length: 551
• Species: Mus musculus
• Alignment Length: 591
• Identity: 137/591 - (23%)
• Similarity: 243/591 - (41%)
• Gaps: 95/591 - (16%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALEN--------- 56
            |.|..::.:.||.||:|.|.::.:......:..|...:|....:|.|.|:...|:|
Mouse     1 MAFQDLIIQIGSLGRFQILHMIFVLICHALSAPHTLLENFTAAIPSHRCWVPILDNDTASDNGSR 65

  Fly    57 -RSFEEIAAIYAPFG---KEASCTR-------LDKIEGDRVTVS---NETC-QRWIYNYDFGFRS 106
             .|.:::..|..|..   :...|.|       |..:.|...||:   .|.| ..|:|:......:
Mouse    66 ILSQDDLLRISIPLDSNLRPDKCRRYIQPQWHLLHLNGTFPTVTEPDTEPCVDGWVYDQSTFLST 130

  Fly   107 MNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLT----T 167
            ...:.:.||.......:.:.::..|..:|....|.|.|:.||.    |...|..:...:|    .
Mouse   131 TVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRK----LIFTCSLLKMAITETCVA 191

  Fly   168 YASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLA 232
            :|.:.:.:...|.:||:.::.......:|:||:.:||.:.: :...:.|...:|..:...|:...
Mouse   192 FAPSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQAL-VMALIFIASGVGQTLLGGLAFAF 255

  Fly   233 GNWRIYLTCSALLQLVVALFYFVV-----QESAQWLITRTNVEGAIARLKHIAHFNGMEVK--AA 290
            .||.     ...|.|.|.:|..::     .|||:|||.....:.::..||..|..|.::..  |.
Mouse   256 RNWH-----HLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNRIKNSGDAL 315

  Fly   291 DFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLS 355
            ..|..:  .|:|.:|.....:.:.: ||.|||||||...|:.|...::.:|...:..|::.:..:
Mouse   316 TLEVVK--TIMKEELEAAQTKPSPL-DLFRTPNLRKRICLLSFVRFVSVMSLLGLLINIQYLSNN 377

  Fly   356 PFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAF 420
            .|::..|:.||..|:..:.....:.:||:.|..:.|...|                  :::|...
Mouse   378 VFLLQCLYGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLG------------------ISILAVV 424

  Fly   421 ALPMRLGI-------------SMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHL 472
            .||..:.|             |...|.|...|:||:||.:|:..:..|.:|.:....:||.|:.|
Mouse   425 FLPQEMQILRVFLSTLGGAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMIL 489

  Fly   473 GTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSK 537
            .|..|:.|.:|..:|........|:||||.|:.||.::.|.|  .|.:|              ||
Mouse   490 TTYSASLPWIIYGILPFLGGLVALLLPETKNQPLPDSIQDIE--NKRKS--------------SK 538

  Fly   538 EATEEV 543
            ||.::|
Mouse   539 EAKKDV 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	126/545 (23%)
Slc22a19	NP_659034.1	MFS_OAT	109..516	CDD:340932	97/437 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		10/37 (27%)