Protein Alignment CG14857 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 559
• Identity: 142/559 - (25%)
• Similarity: 249/559 - (44%)
• Gaps: 77/559 - (13%)

  Fly     1 MDFDQILEKCGSAGRYQ-YLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEE--- 61
            |.|.::|::.|..||:| :..:.|:..|.:.||.:.. :|....||.|.|:...|:|.:.:.
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQNML-ENFSAAVPHHRCWVPLLDNSTSQASIP 64

  Fly    62 -------IAAIYAPFGKEA---SCTRLD----KIEGDRVTVSN------ETCQ-RWIYNYDFGFR 105
                   :.|:..|.|.:.   .|.|..    ::.....|.:|      |.|: .|:|::. .||
Mouse    65 GDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQWQLTESNATATNWSDAATEPCEDGWVYDHS-TFR 128

  Fly   106 SMNAELNW--VCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAV----ILANQCGFVGDF 164
            | .....|  |||......:.||:|..|.|:|....|...||.||.|.:    :|.:..|....|
Mouse   129 S-TIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAAF 192

  Fly   165 LTTYASN-LVQFAIFRCISG-LAATANYYLMFILVLEYLAPKLRNMAIS-GTLGICFCLGALVAP 226
            :.|:... |.:|.:...::| :..||:      |::|:.:.:...:.:: ..||  |..|.::..
Mouse   193 MPTFPLYCLFRFLLASAVAGVMMNTAS------LLMEWTSAQGSPLVMTLNALG--FSFGQVLTG 249

  Fly   227 WLSVLAGNWRIYLTCSALLQLVVALFYFV-------VQESAQWLITRTNVEGAIARLKHIAHFNG 284
            .::....:||       :|||.|:..:|:       :.|||:||||...::..:..|:.:|..|.
Mouse   250 SVAYGVRSWR-------MLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAAVNR 307

  Fly   285 MEVKAADFEAFRRNCIVKRKLSNQPEQT---AGIFDLLRTPNLRK---VSLLVVFTFMLTSLSFN 343
               :.|:.:..... :::..:..:|.:.   |.:..||.||.||.   :|:|..|.|..|   |.
Mouse   308 ---RKAEGDTLTME-VLRSAMEEEPSRDKAGASLGTLLHTPGLRHRTIISMLCWFAFGFT---FY 365

  Fly   344 TISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTE 408
            .::.:::.:|.:.|::.:|..:|..|......||.||:||:......::..||  |.|...|...
Mouse   366 GLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGL--CILSNILVPH 428

  Fly   409 GAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLG 473
            |.....:.|....|....|...|.|:   |:|||.||.:|...:....:||.|.:.:.|.:..||
Mouse   429 GMGVLRSALAVLGLGCLGGAFTCITI---FSSELFPTVIRMTAVGLCQVAARGGAMLGPLVRLLG 490

  Fly   474 TKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLAD 512
            ...:..|.|:..::.:.:....|:||||.|..||.|:.|
Mouse   491 VYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	137/544 (25%)
		MFS	126..470	CDD:119392	91/363 (25%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	137/544 (25%)
		MFS	147..516	CDD:119392	97/395 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843323
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950