Protein Alignment CG14857 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 549
• Identity: 138/549 - (25%)
• Similarity: 238/549 - (43%)
• Gaps: 61/549 - (11%)

  Fly     4 DQILEKCGSAGRYQ----YLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRS------ 58
            |.|||..|....:|    :|:.||.|  |||..  |.....:||.|.|.|....:...|
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSG--AFTPI--YVGIVFLGFTPNHHCRSPGVAELSQRCGWS 65

  Fly    59 -FEEIAAIYAPFGKE------ASCTR---------------LDKIEGDRVTVSNETCQR-WIYNY 100
             .||:.......|..      :.|.|               |..:..:|..:....|:. |:  |
Mouse    66 PAEELNYTVPGLGSAGEVSFLSQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWV--Y 128

  Fly   101 DFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFL 165
            |....|:..|.|.||..::...:.|||..:|..:|....|.|.||.||...:::......:...|
Mouse   129 DTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAISGVL 193

  Fly   166 TTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGIC----FCLGALVAP 226
            ...:.|.....:||.:.||.:.|.:.:.:||:.|::....|.     |:|||    |.:|.|:..
Mouse   194 MAISPNYAWMLVFRFLQGLVSKAGWLIGYILITEFVGLGYRR-----TVGICYQIAFTVGLLILA 253

  Fly   227 WLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAAD 291
            .::....|||.......|......|:::.:.||.:|||::.....|:..:||||..||..|..:
Mouse   254 GVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNGKSVPVS- 317

  Fly   292 FEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSP 356
            .::...:.....||:      ....||:|||.:||.:|::::.:..:|:.:..:..::...|.:.
Mouse   318 LQSLTADEDTGMKLN------PSFLDLVRTPQIRKHTLILMYNWFTSSVLYQGLIMHMGLAGDNI 376

  Fly   357 FVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFA 421
            ::.|...|:|..|:.||..|...|:||:....::.:..| .:|...|.:..:.....:|:    |
Mouse   377 YLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAG-AACLASVFIPDDLQWLKITV----A 436

  Fly   422 LPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKL-AAAPSLILA 485
            ...|:||::.|.:.....:||.||.:|:..:............|:|:|::..|.: ...|.::.|
Mouse   437 CLGRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPFLVYRLTDIWLEFPLVVFA 501

  Fly   486 LLLLTASGCTLMLPETNNRQLPITLADGE 514
            ::.|.|.|..|:||||..:.||.|:.|.|
Mouse   502 VVGLVAGGLVLLLPETKGKALPETIEDAE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	131/535 (24%)
		MFS	126..470	CDD:119392	84/347 (24%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	131/535 (24%)
		MFS	125..492	CDD:119392	95/385 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843827
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950