Protein Alignment CG14857 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_033228.2
• Gene: Slc22a1 / 20517
• MGIID: 108111
• Length: 556
• Species: Mus musculus
• Alignment Length: 554
• Identity: 137/554 - (24%)
• Similarity: 239/554 - (43%)
• Gaps: 57/554 - (10%)

  Fly     4 DQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRS-------FEE 61
            |.:||..|..|.:|....|||..|:.:....|.....:||.|.|.|....:...|       .||
Mouse     5 DDVLEHVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPDHHCRSPGVAELSQRCGWSPAEE 69

  Fly    62 IAAIYAPFGK--EAS----CTR---------------LDKIEGDRVTVSNETCQR-WIYNYDFGF 104
            :.......|.  |||    |.:               |..:..:|..:....|:. |:  ||...
Mouse    70 LNYTVPGLGSAGEASFLSQCMKYEVDWNQSTLDCVDPLSSLAANRSHLPLSPCEHGWV--YDTPG 132

  Fly   105 RSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYA 169
            .|:..|.|.||.||:|..:.||...||..:|:...|.:.||.||...:::......:...||..|
Mouse   133 SSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSLSGVLTAVA 197

  Fly   170 SNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMA-----ISGTLGICFCLGALVAPWLS 229
            .:.....:||.:.|:.:..::...:.|:.|::....|...     ::.|:|:....|...|
Mouse   198 PDYTSMLLFRLLQGMVSKGSWVSGYTLITEFVGSGYRRTTAILYQVAFTVGLVGLAGVAYA---- 258

  Fly   230 VLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEA 294
              ..:||......:|...:..|:|:.|.||.:||:::.....|:..::.||..| .:|..||.:.
Mouse   259 --IPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTQAVRIMEQIAQKN-RKVPPADLKM 320

  Fly   295 FRRNCIVKRKLSNQPEQTAGIF-DLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFV 358
            .   |:.:    :..|:.:..| ||.|||:|||.:|::::.:...::.:..:..:|...|.:.::
Mouse   321 M---CLEE----DASERRSPSFADLFRTPSLRKHTLILMYLWFSCAVLYQGLIMHVGATGANLYL 378

  Fly   359 VFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALP 423
            .|...::|..|:.||..:...|:||......:.|..| .:|.|.:.:..|....||||    |..
Mouse   379 DFFYSSLVEFPAAFIILVTIDRIGRIYPIAASNLVAG-AACLLMIFIPHELHWLNVTL----ACL 438

  Fly   424 MRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLI-HLGTKLAAAPSLILALL 487
            .|:|.::...:.....:||.||.:|:.|:.............:|::: .|.....|.|.::..:|
Mouse   439 GRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALPLILFGVL 503

  Fly   488 LLTASGCTLMLPETNNRQLPITLADGEAFGKGES 521
            .|:|...||:||||....||.|:.:.|..|:.:|
Mouse   504 GLSAGAVTLLLPETKGVALPETIEEAENLGRRKS 537

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	130/533 (24%)
		MFS	126..470	CDD:119392	80/349 (23%)
Slc22a1	NP_033228.2	2A0119	12..525	CDD:273328	130/533 (24%)
		MFS	125..515	CDD:119392	100/410 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843898
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950