DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14857 and Y51A2D.18

DIOPT Version :9

Sequence 1:	NP_650392.1	Gene:	CG14857 / 41791	FlyBaseID:	FBgn0038262	Length:	560	Species:	Drosophila melanogaster
Sequence 2:	NP_507620.2	Gene:	Y51A2D.18 / 180202	WormBaseID:	WBGene00013083	Length:	550	Species:	Caenorhabditis elegans

Alignment Length:	511	Identity:	121/511 - (23%)
Similarity:	209/511 - (40%)	Gaps:	54/511 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 GRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAIYAPFGKEASCTRL 78
            |:|..|:.|....:........:.....|..|:    ..:.:|..|:.:..     |||. |..|
Worm    42 GKYVLLVCLAAELLILPQVSSMFYMMYAGAAPR----VISCDNIVFDSLLE-----GKEI-CFEL 96

  Fly    79 DKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLG 143
            ||:         ..|....:.|.  |||:|.|.|:.||.:...:...|:...|.|.|:..||.:.
Worm    97 DKM---------GNCSHPEFQYQ--FRSINVEYNYFCNTSKLVKNSISVQMFGVLTGSIVFGQIS 150

  Fly   144 DRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLR-- 206
            |..||.....:|:....:|..:...:.||:.|.|.|.|.|.....:..::.:.::|.:..|.|
Worm   151 DSFGRKIGSQVASLGMLIGWLIVVQSRNLLHFTISRTIVGFFTGGSISIINVFIMENIPKKHRMW 215

  Fly   207 -NMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVALFY-FVVQESAQWLITRTNV 269
             ||||:.:..:      .:..:.:.||.:|:.....:|.:.:...||: |.:.||.:||:||..:
Worm   216 INMAITWSPNM------PIYSYFAWLASDWKSLAYINAFMCIPGILFFQFFIHESPRWLVTRGKI 274

  Fly   270 EGAIARL-KHIAHFNGMEVKAADFEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVF 333
            ..|:..| :.:...|...:...|||...|....|.:..|..:.....:.|..||.|...::::.:
Worm   275 SEAVQVLQRQLKTSNQENLIHEDFEENLRMEYAKTQAQNTRKTKFSYYHLFVTPKLAITTIVLAY 339

  Fly   334 TFMLTSLSFNTISRNVEGMGLSPF---VVFSLFAVVVPPSGFIQGLLQSRVGRK--ATAFLAMLC 393
            ::..||:....:..|:|.:..|.:   |...|.......|.....|....:|||  .|:.|.::.
Worm   340 SYCATSIINYGVLFNMEKLSGSIYWNSVYTGLMRYACNLSFGYADLKFKSIGRKFIHTSGLVIIV 404

  Fly   394 TGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQF-------ASELLPTCVRSRG 451
            ..|.......||......|:|         :|:.|.:..::|||.       ::||.||.:|:.|
Worm   405 LSLSLVVGSYALHLNHEMKDV---------IRISILLASSMTSQIYIADGIVSAELFPTPIRTIG 460

  Fly   452 IAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALL-LLTASGCTLMLPETNNRQL 506
            .|.:.|.......:||::.:|.....|.|...:.|. |:.......:||||..|.|
Worm   461 YAFLQLWNRVGVVLSPFIFYLADYWLALPFCFMILFSLIDTFSFECLLPETKGRHL 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	121/511 (24%)
CG14857	NP_650392.1	MFS	126..470	CDD:119392	85/360 (24%)
Y51A2D.18	NP_507620.2	2A0119	24..519	CDD:273328	121/511 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010