Protein Alignment CG14857 and B0252.3

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001021888.1
• Gene: B0252.3 / 174130
• WormBaseID: WBGene00015088
• Length: 484
• Species: Caenorhabditis elegans
• Alignment Length: 524
• Identity: 127/524 - (24%)
• Similarity: 219/524 - (41%)
• Gaps: 101/524 - (19%)

  Fly     4 DQILEKCGSAGRYQYLMILLLGY----IAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAA 64
            |.:|.....:.|:....||:.|.    :|||           |..|..  ..:|.||.||
 Worm    30 DDVLNTLDKSNRHILTCILVCGLAWSPLAFT-----------GLCPSF--VVKASENSSF----- 76

  Fly    65 IYAPFGKEASCTRLDKIEGDRVTVSNETCQRWIYNYDFGFRSMNAELNWVCNDAYKARIGQSLFF 129
                                 :.|::|        :|     :..:.:|:      |....:.:.
 Worm    77 ---------------------IGVADE--------FD-----LTGDASWL------AESTTTFYM 101

  Fly   130 LGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFAIFRCISGLAATANYYLMF 194
            :|:::|......|.|..||:...:.......||..::.::::::.|.|.|.|.|:..||.....:
 Worm   102 VGNMIGGMFIPPLADHYGRLPVFVATVLLMAVGGMISAFSTSIMMFCIMRMIHGIFYTAAGLAGW 166

  Fly   195 ILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTCSALLQLVVA-LFYFVVQE 258
            :|..|....:|| ...|...|:.:.:||.....|:.:..:||..:.|.::..:.|| |.|..|.|
 Worm   167 VLGYENTPLRLR-FFTSVYFGVMWVVGACFLGLLAYILPDWRYLMFCISVPNIFVALLIYMTVPE 230

  Fly   259 SAQWLITRTNVEGAIARLKHIAHFNGMEVKAADF--------EAFRRNC--IVKRKLSNQPEQTA 313
            |..:|::....|...|.|:.|....| ::.|:|.        .:|:..|  :.|.|:..
 Worm   231 SLHFLVSSQQNEKIEAWLEKIRGPKG-DISASDIVEDRDENGSSFKTLCREMWKHKMFI------ 288

  Fly   314 GIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQ 378
             ::.|:.|      .:.:|.||:...|:|  .|.|:.|   :.::.|.|.::|..|:.....:..
 Worm   289 -VYVLVMT------YIWIVDTFIYFGLAF--YSTNLAG---NLYLNFVLMSLVEAPAYIFSPIFM 341

  Fly   379 SRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELL 443
            ::.|||.......:..||  ..||:.||:|....:..||..||      ||..:.....||||:.
 Worm   342 NKYGRKVLISGTHIIAGL--SFLGIVLSSEAWHIHFWLLGKFA------ISCSFMSIYMFASEIF 398

  Fly   444 PTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPI 508
            ||..|::.|......:.....:||||.||....|.||::.|:|:.::....||:||||.|.:||.
 Worm   399 PTDGRNKCIGFCETLSRFGGMLSPYLSHLTAVHALAPAITLSLIAVSGGLLTLILPETLNTKLPS 463

  Fly   509 TLAD 512
            |:|:
 Worm   464 TIAE 467

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	123/512 (24%)
B0252.3	NP_001021888.1	MFS_SLC22	73..454	CDD:340875	105/453 (23%)