Protein Alignment CG14857 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 442
• Identity: 116/442 - (26%)
• Similarity: 180/442 - (40%)
• Gaps: 77/442 - (17%)

  Fly   112 NW--VCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTT------- 167
            ||  ||.|.:|..:.|....||.|:|....|...||.|| |||.:|:.      .|||
Human     8 NWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGR-RAVFVASL------VLTTGLGASEA 65

  Fly   168 YASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLA 232
            .|::.....:.|.:.|.........:::..||...|..| :|.|...|:...:|.|:.|.|:.|.
Human    66 LAASFPTLLVLRLLHGGTLAGALLALYLARLELCDPPHR-LAFSMGAGLFSVVGTLLLPGLAALV 129

  Fly   233 GNWRIYLTCSALLQLVVALFY---FVVQESAQWLITRTNVEGAIARLKHI----AHFNGMEVKAA 290
            .:||:.....||:..::.||:   .:..||..||:    ..|.:||.:.|    |..:|:....:
Human   130 QDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLL----ATGQVARARKILWRFAEASGVGPGDS 190

  Fly   291 DFE--AFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFML---TSLSF-NTISRNV 349
            ..|  :......:....|.||...:.: .||||....:..|::.|:.::   ...|| .:::..|
Human   191 SLEENSLATELTMLSARSPQPRYHSPL-GLLRTRVTWRNGLILGFSSLVGGGIRASFRRSLAPQV 254

  Fly   350 EGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQK-- 412
            ....|..|:...|.|..:.   |:. |.....||:....|..:.|||.|..|     ..|||.
Human   255 PTFYLPYFLEAGLEAAALV---FLL-LTADCCGRRPVLLLGTMVTGLASLLL-----LAGAQYLP 310

  Fly   413 --NVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTK 475
              .|..|....|.....:|   .::|.||:|:.||.:|..|:..|    .||.|:..
Human   311 GWTVLFLSVLGLLASRAVS---ALSSLFAAEVFPTVIRGAGLGLV----LGAGFLGQ-------- 360

  Fly   476 LAAAP-------------SLILALLLLTASGCTLMLPETNNRQLPITLADGE 514
             ||.|             .::.|.|.:.|..|.|:|||:.:|.||.:|.|.:
Human   361 -AAGPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDAD 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	114/435 (26%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	102/411 (25%)