Protein Alignment CG14857 and SLC22A9

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 557
• Identity: 139/557 - (24%)
• Similarity: 236/557 - (42%)
• Gaps: 72/557 - (12%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALEN--------- 56
            |.|..:|...|...|:|.|..:.|...|..|.:|:..:|...|:|.|.|:...|:|
Human     1 MAFQDLLGHAGDLWRFQILQTVFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTG 65

  Fly    57 -RSFEEIAAIYAPFG---KEASCTR-------LDKIEGDRVTVSN---ETC-QRWIYNYDFGFRS 106
             .|.:.:..|..|..   :...|.|       |..:.|.....|:   |.| ..|:|:......:
Human    66 ALSQDALLRISIPLDSNMRPEKCRRFVHPQWQLLHLNGTFPNTSDADMEPCVDGWVYDRISFSST 130

  Fly   107 MNAELNWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGR-------VRAVILANQCGFVGDF 164
            :..|.:.||:......:.:.:|..|.::|....|.|.||.||       ...|.:...|..:...
Human   131 IVTEWDLVCDSQSLTSVAKFVFMAGMMVGGILGGHLSDRFGRRFVLRWCYLQVAIVGTCAALAPT 195

  Fly   165 LTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGIC-FCLGALVAPWL 228
            ...|.|       .|.:||:||.:......:|:.|:...:.:.|.|  |||:| ..:..:....|
Human   196 FLIYCS-------LRFLSGIAAMSLITNTIMLIAEWATHRFQAMGI--TLGMCPSGIAFMTLAGL 251

  Fly   229 SVLAGNWRIYLTCSALLQLVVALFYFVV-------QESAQWLITRTNVEGAIARLKHIAHFNGME 286
            :....:|.|       |||||::.|||:       .|||:|||.....|..:..|:..||.:||:
Human   252 AFAIRDWHI-------LQLVVSVPYFVIFLTSSWLLESARWLIINNKPEEGLKELRKAAHRSGMK 309

  Fly   287 VKAAD---FEAFRRNCIVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRN 348
             .|.|   .|..:..  :|::|....::...:.::|..||:.|...|:.||.....:::..::.:
Human   310 -NARDTLTLEILKST--MKKELEAAQKKKPSLCEMLHMPNICKRISLLSFTRFANFMAYFGLNLH 371

  Fly   349 VEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKN 413
            |:.:|.:.|::.:||..|:..:..:.......:.|:|:..|.|..  |..|.|.:....:..|
Human   372 VQHLGNNVFLLQTLFGAVILLANCVAPWALKYMNRRASQMLLMFL--LAICLLAIIFVPQEMQ-- 432

  Fly   414 VTLLLAFALPMRLGIS-MCYTVTSQFASELLPTCVRSR--GIAAVHLAAAGASFVSPYLIHLGTK 475
             ||....| .:.||.| :..|:.....:|::||.:|:|  ||.|.....|||  ::|.::.|...
Human   433 -TLREVLA-TLGLGASALANTLAFAHGNEVIPTIIRARAMGINATFANIAGA--LAPLMMILSVY 493

  Fly   476 LAAAPSLILALLLLTASGCTLMLPETNNRQLPITLAD 512
            ....|.:|..:....:....|:||||.|:.|..|:.|
Human   494 SPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	134/542 (25%)
SLC22A9	NP_543142.2	MFS_OAT	109..517	CDD:340932	106/434 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		1/3 (33%)