Protein Alignment CG14857 and slc22a16

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_002936981.2
• Gene: slc22a16 / 100488673
• XenbaseID: XB-GENE-961385
• Length: 567
• Species: Xenopus tropicalis
• Alignment Length: 608
• Identity: 130/608 - (21%)
• Similarity: 244/608 - (40%)
• Gaps: 95/608 - (15%)

  Fly     4 DQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEEIAAIYAP 68
            :::.:..|..||:|.|:.....:.|.:..:||.:...|...|:..|       |:.|.|:::..|
 Frog     2 ERLFDYVGHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFIC-------RAPENISSVLLP 59

  Fly    69 FGKEASCTRLDKI-----EGDRVTVSNET--------CQRW--------IYNYD----------- 101
               .||..||:.:     ..|.:.|..|.        |.|:        .|:||
 Frog    60 ---NASTLRLEDVWELWTPKDYLVVKQENGDIWELNQCSRFKRENTSYLTYSYDGNKTLFSCSNG 121

  Fly   102 FGFRSMNAE----LNW--VCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGF 160
            :.:.:.|.|    .:|  ||...:.|::.|..|..|.|:|...||.:.||:||...:.|.:...|
 Frog   122 YYYDNTNLESSIVTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLTSTGQF 186

  Fly   161 VGDFLTTYASNLVQFAIFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVA 225
            :......:..:...|.|.|.:..:.::..|.::|:.|.||:..|.|:.| |..:...|.:|.::.
 Frog   187 LFGIAVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARSWA-SMHVHAFFAVGVMIV 250

  Fly   226 PWLSVLAGNWRIYLTCSALLQLVVALFYFVVQESAQWLITR---TNVE---GAIARLKHIAHFNG 284
            ..:..|...|.:|....:|..|...|..:::.|:..||.::   ..||   |.|.:...|:
 Frog   251 SLVGFLVRTWWMYQIILSLTTLPFVLCCWMLPETPFWLYSQGKHKEVEKLIGTIEKWNKIS---- 311

  Fly   285 MEVKAADFEAFRRNCIVK--RKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISR 347
            ...|.::.      |.|:  :|......:...:.||....:..:.::.|...:...||.:...:.
 Frog   312 TPCKLSEL------CSVQETQKTEMDTLKKHSVLDLFYNWSFARRTVTVWLIWFTGSLGYYVFAL 370

  Fly   348 NVEGMGLSPFVVFSLFAVVVPPSGFIQGLLQSRVGRKAT--AFL---AMLCTGLLSCALGVALST 407
            |...:|.:.::...|.:.|..||..:......::||:.|  .||   |::|        |:.:..
 Frog   371 NSVNLGGNEYLNLFLTSAVEIPSYIVACFGMDKIGRRNTLAPFLILSAVIC--------GIIMLI 427

  Fly   408 EGAQKNVTLLLAFALPMRLGISMCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHL 472
              .|.:.|:.:|.::..:..|::.:.:...:.:||.||.|||..:.:..:.....|.|:|:.::|
 Frog   428 --PQDHSTVTIAMSMGGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYL 490

  Fly   473 GTKLAAAPSLILALLLLTASGCTLMLPETNNRQLPITLADGEAFGKGESMLSFDCWRRHDDDVSK 537
            .......|.:::.::.......||.||||....|..|:.:....|....:..           .|
 Frog   491 TDVWIFMPQMLVGIMAFLTGVLTLKLPETLGVPLTSTIEEAAEMGTNNRITK-----------RK 544

  Fly   538 EATE--EVRLHQLNGQTKSETEA 558
            ..||  .|.:..:|..|...|.|
 Frog   545 SITECKGVLMENVNPSTTDNTTA 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	120/548 (22%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	88/426 (21%)