Protein Alignment CG14857 and slc22a6

DIOPT Version :10

• Sequence 1: NP_650392.1
• Gene: CG14857 / 41791
• FlyBaseID: FBgn0038262
• Length: 560
• Species: Drosophila melanogaster
• Sequence 2: XP_002937540.1
• Gene: slc22a6 / 100487511
• XenbaseID: XB-GENE-5842250
• Length: 552
• Species: Xenopus tropicalis
• Alignment Length: 546
• Identity: 138/546 - (25%)
• Similarity: 243/546 - (44%)
• Gaps: 47/546 - (8%)

  Fly     1 MDFDQILEKCGSAGRYQYLMILLLGYIAFTTTVHYYSQNIIGFVPQHWCYHEALENRSFEE---- 61
            |.|.:|||..|..||||.:.::||....|....|...||....:|:|.|.    .|.||||
 Frog     1 MAFQEILESIGGMGRYQVIHVVLLSLPVFMLASHNLMQNFTAAIPRHRCQ----INGSFEETNFT 61

  Fly    62 ---IAAI--YAPFGKEASCTR---------LDKIEGDRVTVSNETC-QRWIYNYDFGFRSMNAEL 111
               :.|:  ..|.|:.:.|.|         :|....:...:..||| ..|:|::.....::..:.
 Frog    62 GPWLRALVPMKPTGEFSKCLRYTTPQYHLLMDNFTQNVDELETETCVDGWVYDHSEFASTIITQW 126

  Fly   112 NWVCNDAYKARIGQSLFFLGSLMGTFTFGVLGDRIGRVRAVILANQCGFVGDFLTTYASNLVQFA 176
            :.|||.....::.||::..|.|:|:..||.|.|:.||....|.:|....|......::.|.:.:.
 Frog   127 DLVCNHRRMRQVAQSIYMAGVLVGSVVFGGLSDKFGRRPLNIWSNLQMSVTGICAAFSPNYIWYC 191

  Fly   177 IFRCISGLAATANYYLMFILVLEYLAPKLRNMAISGTLGICFCLGALVAPWLSVLAGNWRIYLTC 241
            |||.::|.|.:......:.|::|::....|....:.| |.|:.:|.||...|:.:..:|.
 Frog   192 IFRFLTGTALSGIVLNSYSLIVEWIPTGNRAFTSTAT-GYCYTMGQLVLVGLAFMIRDWH----- 250

  Fly   242 SALLQLVVAL---FYFV----VQESAQWLITRTNVEGAIARLKHIAHFNGMEVKAADFEAFRRNC 299
              .|||..:|   |||:    :.||.:||:.....|.|...||.:|..||.:.............
 Frog   251 --WLQLAASLPFFFYFLYSWWIPESGRWLVLSGKPEVACKALKKVAKINGKKEAGEKLTVEVLKS 313

  Fly   300 IVKRKLSNQPEQTAGIFDLLRTPNLRKVSLLVVFTFMLTSLSFNTISRNVEGMGLSPFVVFSLFA 364
            .::|::|.....|..:.||:|||.:|::|..:..|:..||.::..::.:::..|:|.:::..:|.
 Frog   314 SMQREISASKHSTYSVLDLVRTPVVRRISFCISCTWFSTSFAYYGLALDLQSFGVSIYIIQIIFG 378

  Fly   365 VVVPPSGFIQGLLQSRVGRKATAFLAMLCTGLLSCALGVALSTEGAQKNVTLLLAFALPMRLGIS 429
            .|..|:.|....:.:.:||:....|.::..|     :.:.::....|...|:..:.|:..:..::
 Frog   379 TVDIPAKFFSYFVMTYIGRRVLQALTLILAG-----IAILVNICVPQDYQTVRTSMAVFGKGCLA 438

  Fly   430 MCYTVTSQFASELLPTCVRSRGIAAVHLAAAGASFVSPYLIHLGTKLAAAPSLILALL--LLTAS 492
            ..:.....:..||.||.:|..|:....:.|.....::|.....|....:.|.:|...|  |...:
 Frog   439 ASFNCLFLYTGELYPTVIRQSGMGLGTMMARLGGIIAPLAQMTGDIYHSLPLIIFGCLPILSGIA 503

  Fly   493 GCTLMLPETNNRQLPITLADGEAFGK 518
            ||  .||||....||.|:.|.|:..|
 Frog   504 GC--FLPETLGVPLPETIEDVESSDK 527

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14857	NP_650392.1	2A0119	11..509	CDD:273328	129/525 (25%)
slc22a6	XP_002937540.1	MFS_SLC22A6_OAT1_like	102..508	CDD:341004	98/420 (23%)