Protein Alignment CG14856 and Slc22a7

DIOPT Version :10

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_445989.2
• Gene: Slc22a7 / 89776
• RGDID: 621699
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 551
• Identity: 131/551 - (23%)
• Similarity: 237/551 - (43%)
• Gaps: 59/551 - (10%)

  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWC---------YHEQ--L 56
            |.|:::|.|.|....:|...|.|..|...::..|:.....:..||.|.|         .|:.  |
  Rat     1 MGFEDLLDKVGGFGPFQLRNLVLMALPRMLLPMHFLLPVFMAAVPAHHCALPGAPANLSHQDLWL 65

  Fly    57 ENRSYAEIAAIYAPFKRPSCTRLA------SINMDGSNATASSE--------PCNR-WIYHYDHG 106
            |.....|....::     ||.|.|      ::.: |:..:.|.|        ||:: |  .||..
  Rat    66 EAHLPRETDGSFS-----SCLRFAYPQTVPNVTL-GTEVSNSGEPEGEPLTVPCSQGW--EYDRS 122

  Fly   107 FISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSAT 169
            ..|......|  ||......::..:.||:|.:.|.:::|.|.||.||.:.:::|.....:....:
  Rat   123 EFSSTIATEWDLVCQQRGLNKITSTCFFIGVLVGAVVYGYLSDRFGRRRLLLVAYVSSLVLGLMS 187

  Fly   170 IFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVW 234
            ..:...:.|..:|.::|.|....:.::..|.||::....|:|. .:...||:..|::..:..|..
  Rat   188 AASINYIMFVVTRTLTGSALAGFTIIVLPLELEWLDVEHRTVA-GVISTVFWSGGVLLLALVGYL 251

  Fly   235 LGSWRSFMVWTALPQLLVTGFYFL--IQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYEL 297
            :.|||..::...||  .|.|...:  :.|||:||:|:...:.|:..|...||.|.|.|.|.
  Rat   252 IRSWRWLLLAATLP--CVPGIISIWWVPESARWLLTQGRVEEAKKYLLSCAKLNGRPVGEG---- 310

  Fly   298 FRQHCKTKESEARSQMSMQKQA----RLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGL 358
                  :...||.:.:...::|    ..:|.|:..:||...:...:|:..|...|..::.:|.||
  Rat   311 ------SLSQEALNNVVTMERALQRPSYLDLFRTSQLRHISLCCMMVWFGVNFSYYGLTLDVSGL 369

  Fly   359 SISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMV 423
            .::.:....||.....||.|....:.:..||:.|. ..|.....:|..|.:|::..|:...|.:|
  Rat   370 GLNVYQTQLLFGAVELPSKIMVYFLVRRLGRRLTE-AGMLLGAALTFGTSLLVSLETKSWITALV 433

  Fly   424 CLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSII 488
              ::...|..:..|.:.: .::||.||.:|.:||.:..:.....:.::|....||..:.....:.
  Rat   434 --VVGKAFSEAAFTTAYL-FTSELYPTVLRQTGLGLTALMGRLGASLAPLAALLDGVWLLLPKVA 495

  Fly   489 TCILLLVSAWICLLLSETRNKKLPLTLAEGE 519
            ...:.||:|...|||.||:..:||.|:.:.|
  Rat   496 YGGIALVAACTALLLPETKKAQLPETIQDVE 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	125/534 (23%)
Slc22a7	NP_445989.2	2A0119	11..521	CDD:273328	125/534 (23%)