DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and GIT1

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_010022.1	Gene:	GIT1 / 850462	SGDID:	S000000695	Length:	518	Species:	Saccharomyces cerevisiae

Alignment Length:	512	Identity:	97/512 - (18%)
Similarity:	168/512 - (32%)	Gaps:	164/512 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly   103 YDHGFISMNADLNWVC-----DDAYKARVG---QSLFFVGSMCGTLLFGLLGDRIGRIKAVVLAN 159
            |.:|.:||   ||.|.     ...|.::|.   .:...||.:.|....|:..|...|...:::|.
Yeast    60 YVNGSMSM---LNKVFVMEYGKKNYSSKVSTRVSNAALVGIIFGQFFMGIAADYYSRKSCILVAT 121

  Fly   160 CCGFLGDS--ATIFAET------LLTFSASRFVSGLAAE-----------ANSY----------- 194
            ....:|.:  |.....|      :||........|:.||           ||.|
Yeast   122 AILVIGSALCAASHGTTVPGMFWMLTVMRGLVGIGVGAEYPTSTLSANESANEYTTTKRGGILVM 186

  Fly   195 --------------LMFILV---------LEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLG 236
                          ::|::|         ||.:..|:.::|....:.|||      ..|:.....
Yeast   187 VTNLPLAFGGPFATIIFLIVYKICSGTKHLEAIWRTVFAIGCFWPLSVFY------FRWKTATTE 245

  Fly   237 SWRSFMVWTALPQLLVTGFYF--LIQESAQWLVTRQDF----DG--AELRLRRVAKFNRRDVSEA 293
            .:....:...:|..|...||:  |:.....|.:  .||    :|  :...:..|.|.....|..|
Yeast   246 VYEKGRIKRNIPYFLALKFYWKRLLGTCGTWFM--YDFVTFPNGIFSSTIISSVIKDQNDLVKVA 308

  Fly   294 DYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVT-------VVFSIVTLC-YNT 350
            ::.|.        ....:.:.:...|.|.|       |:...|..       ::|.::..| |:.
Yeast   309 EWNLL--------LGVLAVLGVPIGAYLSD-------RIGRKYTLMFGFSGYIIFGLIIGCAYDQ 358

  Fly   351 MSRNVEGLSISP-FVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFW 414
            :.:      |:| |::|..|...|..:|          ......|:|..|:.  ||..|:.
Yeast   359 LKK------ITPLFIIFYAFMNMLGNAG----------PGDMLGVISSEASA--TAVRGVF---- 401

  Fly   415 TQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTC---VRSS-GLAVIHVTAAALSFISPFIL 475
                            :|:|..||   :|.:.:...|   :|.: |.....:.||....|...|
Yeast   402 ----------------YGLSAVTG---KIGSVVGVECFQPIRDNLGARWTFIIAAICGLIGIII- 446

  Fly   476 HLDTYFRAASSIITCIL---------LLVSAWICLL-LSETRNKKLPLTLAEGEEFG 522
               |||....|:.:.::         |:.:.|...: ..||..:.:..|: |.||.|
Yeast   447 ---TYFFVPHSLESDLMKQDVEFHNYLVSNGWTGKMGFDETDEESMVRTI-EVEENG 499

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	92/502 (18%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	81/457 (18%)
GIT1	NP_010022.1	MFS_PhT	48..454	CDD:340922	87/464 (19%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000