DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14856 and OCT5

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_178059.1	Gene:	OCT5 / 844279	AraportID:	AT1G79410	Length:	515	Species:	Arabidopsis thaliana

Alignment Length:	532	Identity:	115/532 - (21%)
Similarity:	217/532 - (40%)	Gaps:	64/532 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MDFDEILVK-CGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAA 66
            :.||:||.| ..|....|::.:.|.||.:...|:..|........|...|....:.|
plant    23 LTFDKILEKSLSDFGFSQFLQIVLVGLALTFDSQQIFITVFTDAYPTWHCLDHTICN-------- 79

  Fly    67 IYAPFKRPSCTRLASINMDGSNATASSEPCNRWIYHYDHGF--ISMNADLNWVCDDAYKARVGQS 129
                   |:.|.:..|            |.:.|  .:|.||  .|:.::.:..|..::...:..|
plant    80 -------PATTDICKI------------PRSAW--DWDGGFKGKSVISEFDLECSSSFLRSLPSS 123

  Fly   130 LFFVGSMCGTLLFGLLGD-RIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANS 193
            .|:|||:.|.::..::.| .:||.:.:..::....|...:...:..:..:|..:||.|.|.....
plant   124 TFYVGSIVGGVVLAMIPDGSLGRKQLLFFSSFAMSLTGISIFLSSNIWIYSFLKFVIGFARSQTG 188

  Fly   194 YLMFILVLEYVSPTMRSVGLNLTMCVF--YGLGMICASWQGV-WL---GSWRSFMVWTALPQLLV 252
            ....:|:.|.:|...|.   ..||..|  :.||.:  |..|: :|   .||:...:.|::|..:.
plant   189 TYALVLISERISTKWRP---RATMVPFTLFVLGFM--SLSGIAYLVRHASWKVLYLCTSIPAGIH 248

  Fly   253 TGF-YFLIQESAQWL-VTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKES-EARSQMS 314
            :.| ||...||.:|| :..::.:..|: |:|::..||..:......|     :.||: |..|..|
plant   249 SIFIYFFALESPRWLHLEGKNKEAIEV-LKRISPANRGYLESVSSRL-----RPKETLEQTSSYS 307

  Fly   315 MQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLPPSGIF 379
            ::      |.|.:.....|:..|.::...:.:.|..:...|..:.::.::..:|.|:...|:.:.
plant   308 IK------DLFIIKWAFRRVTLVMIIMFGLGMSYYGVPLAVRDIKVNIYMSEALNAMVELPTFVV 366

  Fly   380 QTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQI- 443
            ...:.:.|.|:.:.:|:.    |:...:|:|....:.:..|.:...|.:..|..:....:.|.|
plant   367 TPILLEQFSRRSSVLVNC----LIGGASGVLCFVMSLYGRTKIAFALELGSFFCARIGFNLMAIY 427

  Fly   444 STELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAWICLLLSETRN 508
            ..||.|||||:|...::...........|.|..|.....:.|..:....:.......|||.||:.
plant   428 LVELFPTCVRNSATMMLRQALVVGGACCPLIASLGRNVPSLSFAVFGFAMSGLGLFALLLPETKG 492

  Fly   509 KKLPLTLAEGEE 520
            ..|..|:.|.|:
plant   493 LSLCDTMEEQEQ 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	107/513 (21%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	82/384 (21%)
OCT5	NP_178059.1	MFS_OCT_plant	83..488	CDD:340936	92/439 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010