DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14856 and OCT3

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_173089.1	Gene:	OCT3 / 838209	AraportID:	AT1G16390	Length:	518	Species:	Arabidopsis thaliana

Alignment Length:	550	Identity:	115/550 - (20%)
Similarity:	213/550 - (38%)	Gaps:	86/550 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 DEILVKC-GDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAAIYA 69
            :|.:.:| ||....|::..||.....|..::..|   :..|......:|
plant    26 EETIERCIGDFGWAQFLQAALVSFAWFFDAQQTF---ITVFTDSQPMWH---------------- 71

  Fly    70 PFKRPSCTRLASINMDGSNATASSEPC----NRWIYHYD-HGFISMNADLNWVCDDAYKARVGQS 129
                  |..  |..:|....|:||..|    ..|.:..: |  :|:.::....|..::......|
plant    72 ------CDN--SDRVDSVCNTSSSNLCTLPNQTWSWDLNPH--VSIISEWGLQCAGSFLKGFPAS 126

  Fly   130 LFFVGSMCGTLLFGLLGD-RIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANS 193
            .||:|.:.|.|....|.| .:||...::|:.....|....|.|:.::..::..||::|.......
plant   127 SFFLGCLIGGLALSTLADSSLGRKNMLLLSCLIMSLSSMLTAFSTSIWVYAFLRFLNGCGRATIG 191

  Fly   194 YLMFILVLEYVSPTMR-SVGLNLTMCV---FYGLGMICASWQGVWLGSWRSFMVWTALPQL---- 250
            ....:|..|.|....| .||.....|.   |..|.|:....:|   .|||:..|||::|.|
plant   192 TCALVLSTELVGKKWRGQVGAMGFFCFTLGFLSLPMLGYINEG---NSWRNLYVWTSIPTLIYCC 253

  Fly   251 LVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHC-KTKESEARSQMS 314
            ||..|   ::||.:||:.:...:.|...|:.:|       |.|....|...| :.:..:::|...
plant   254 LVRSF---VRESPRWLIVKGRKEEAVSILQSIA-------SNAITMSFTNLCFEVENDQSKSNPD 308

  Fly   315 MQKQARLI--DSFKLPRL--------RLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLF 369
            :....:::  .|:...||        .:.::|..:..::..|.:|...    |:..:....|..|
plant   309 VYDALKILVRKSWSFRRLLAAMVVGFGIGMVYYGMPLALTNLNFNLYL----GVVFNALSEFPAF 369

  Fly   370 ALTLPPSGIFQTQVQKHFGRKFTSVVSMTA-TGLMTATTGILLAFWTQHSATVMVCLLLMCRFGI 433
            .:|.    .|..::.:.     .:::..|| :|:.:|    |:|...|...::.:.|.|:..|..
plant   370 LITF----FFIDKINRR-----DALIGFTALSGISSA----LIAVLGQQLGSLQIVLELVSFFSA 421

  Fly   434 SVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAW 498
            ......|:..:.|:.|||||:|.::::..........||.::......:..|..:..:::.:...
plant   422 CTAFNMTLIYTIEMFPTCVRNSAISMVRQALVFGGVFSPVMVAAGRENQFWSYGLFGLIIGLCGL 486

  Fly   499 ICLLLSETRNKKLPLTLAEGEEFGKGERMF 528
            ....|.|||...|..|:.|.|.....:|.|
plant   487 FVFGLPETRGSVLCDTMDEEEYKTLAKRQF 516

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	108/526 (21%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	83/394 (21%)
OCT3	NP_173089.1	MFS_OCT_plant	87..492	CDD:340936	89/436 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.020