Protein Alignment CG14856 and Slc22a23

DIOPT Version :10

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001028339.1
• Gene: Slc22a23 / 73102
• MGIID: 1920352
• Length: 689
• Species: Mus musculus
• Alignment Length: 659
• Identity: 147/659 - (22%)
• Similarity: 252/659 - (38%)
• Gaps: 165/659 - (25%)

  Fly     1 MAMDFDEILVKC--GDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWC----YHEQLENR 59
            :.:|:|..::..  |....||..|:.|..:....:....|:.:.:...||.||    ...:|...
Mouse    76 LLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPDFWCRGAGKGTELAGA 140

  Fly    60 S----YAEIAAIYAPFKRPSCTRLASINMDGSNATASSEP----------------CNRWIYHYD 104
            :    :.::....:|...|..|  ||.....:.:.:|..|                |:.|.|...
Mouse   141 TVTGRWGDMGNWTSPSATPFST--ASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCDCHAWDYGIR 203

  Fly   105 HGFISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDS 167
            .|.| .|....|  |||:.:|..:.:....||.:.|.|:.|.:.|.:|| :.|:|.:....|...
Mouse   204 TGLI-QNVVSKWDLVCDNTWKVHIAKFSLLVGLIFGYLITGCIADWVGR-RPVLLFSTIFILIFG 266

  Fly   168 ATIFAETLLT-FSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFY---------- 221
            .|:.....:| ||..||..|.........::.|.:|...|..|.:   :||...:
Mouse   267 LTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFI---ITMVASFVAMAGQFLMP 328

  Fly   222 GLGMICASWQGVWLGSWRSFMVWTAL---PQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVA 283
            ||..:|..||           |..||   |.||:..::.:..||.:||:..|.|:.|:..:
Mouse   329 GLAALCRDWQ-----------VLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLI---- 378

  Fly   284 KFNRRDVSEADYELFRQHCKTKESEARSQM-SMQKQARLIDSFKLPRLRLRLIYVTVV------F 341
                       ..|.:::|.:.||:.:..| .::|:        |.|...::..|.||      .
Mouse   379 -----------LYLTQKNCVSPESDIKGVMPELEKE--------LSRRPKKVCIVKVVGTRNLWK 424

  Fly   342 SIVTLCYNTM---------SRNVEGLSIS-PFV------MFSLFALTLPPSGIFQTQVQKHFGRK 390
            :||.||.|::         :|::.|..:. |.:      .:::.::.| .|.:....|.|..||:
Mouse   425 NIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIAL-ASCLAMCLVVKFLGRR 488

  Fly   391 --------FTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQIS--- 444
                    .|::.|:...||:.     |:..::||..:.   |.|....|:|.:......|:
Mouse   489 GGLLLFMILTALASLLQLGLLN-----LIGKYSQHPDSE---LQLKLAVGMSDSVKDKFSIAFSI 545

  Fly   445 -----------------TELMPTCVRSSGLAVIHVTAAALSFISPFI-LHLDT-YFRAASSIITC 490
                             .|:.||.:|..||.::..:|......:|.| ||... ||........|
Mouse   546 VGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACC 610

  Fly   491 ILLLVSAWIC-LLLSETRNKKLPLTLAEGEEF--------GKGERMFDFMRSFKK--ADQHDLSA 544
            .|:.:   || |||.|:||:.||..:|.||.:        .|||:......:..|  :..||::|
Mouse   611 TLICI---ICILLLPESRNQNLPENIANGEHYTRQPLLPHKKGEQPLLLTNAELKDYSGLHDVAA 672

  Fly   545 DTIEKLMGD 553
                  :||
Mouse   673 ------VGD 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	133/594 (22%)
Slc22a23	NP_001028339.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/27 (19%)
		MFS_SLC22A23	187..608	CDD:341002	103/468 (22%)