Protein Alignment CG14856 and Slc22a16

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 598
• Identity: 133/598 - (22%)
• Similarity: 237/598 - (39%)
• Gaps: 90/598 - (15%)

  Fly     5 FDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWC----------YHE----Q 55
            ||.|    |...|:|.:|..:..........||.:...:..:|:|.|          :|.    :
Mouse    10 FDHI----GHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAVFHNVSAWR 70

  Fly    56 LENRSYAEIAAIYAP---------------FKRPSCTRLASINMDGSNATAS----SEPC-NRWI 100
            ||     :|.|:.:|               ::...|:|....|........|    ..|| :.::
Mouse    71 LE-----DILALRSPEHKDHIMVELQDGEIWELTRCSRTWRENTSHLGYEYSGYKHDSPCFDGYV 130

  Fly   101 YHYDHGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLG 165
            |.......|...:.|.|||..:.||:.|.|...|.|.|::.|..|.||.||..|:...:...|..
Mouse   131 YDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMALWCTSIGVFFF 195

  Fly   166 DSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYV---SPTMRSVGLNLTMCVFYGLGMIC 227
            ..|::|....|:|..:||...:|:.....::|:.|:|.:   :.|..|:.||    .|:.:|.:.
Mouse   196 GIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLN----TFFAIGAML 256

  Fly   228 ASWQGVWLGSWRSFMVWTALPQLLVTGFY---FLIQESAQWLVTRQDFDGAELRLRRVAKFNRRD 289
            .:.....|.:|..:.:   :..::.|.|.   :::.|:..||::...:..|:..:..:|.:|:..
Mouse   257 VALASYLLKTWWLYQI---ILCIVTTPFILCCWMLPETPFWLLSEGRYKEAQGTVDTMAVWNKSS 318

  Fly   290 ----VSEADYELFRQHCKTKESEARSQMSMQKQARLIDSF-KLPRLRLRLIYVTVVFSIVTLCYN 349
                |.....::.|.|.|       |..|::|. ||.|.| .|...::.|| |.:.:....|.|.
Mouse   319 SCDLVELLSLDVTRSHNK-------SPHSIRKH-RLADLFHNLDVAKMTLI-VWLDWFTANLGYY 374

  Fly   350 TMSRNV-EGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAF 413
            ...:.| ......|..:..:.|:.: |:.|......|..||:.|.::.:    |:::.|.:|...
Mouse   375 MFGKEVIRRKENEPLYLLLVGAMEI-PAYICLCIWLKRVGRRKTMLLFL----LVSSLTCMLHVV 434

  Fly   414 WTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLD 478
            ......|....:.|:.:..||.........:.||.||.||...:...::.:...|...||..|..
Mouse   435 MPSDYKTAKRMVALLVKSVISSVFAFIYLYTAELYPTTVRCLAVGSSNMVSHVSSIFIPFTSHFS 499

  Fly   479 TYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEE--------FGKG-----ERMFDF 530
            ..:.....|:..||.::|..:.|.|.||::..:..|....|:        .|:|     || :|.
Mouse   500 KVWIFLPQILFGILAILSGLLSLKLPETQDTPMKSTWETTEQQVPENKDSLGEGPPDSFER-WDS 563

  Fly   531 MRSFKKADQHDLS 543
            .|:...|::..||
Mouse   564 SRALSFAERWGLS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	119/546 (22%)
		MFS	129..503	CDD:119392	86/385 (22%)
Slc22a16	NP_081848.1	2A0119	14..535	CDD:273328	119/546 (22%)
		MFS	163..525	CDD:119392	85/382 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		4/29 (14%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843693
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940