DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and LOC685081

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_008764922.2	Gene:	LOC685081 / 685081	RGDID:	1583222	Length:	621	Species:	Rattus norvegicus

Alignment Length:	536	Identity:	123/536 - (22%)
Similarity:	243/536 - (45%)	Gaps:	39/536 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSY----AEIA 65
            |.:::.:.||...:|..:..|.|:..|:.:...|:|..:.....|.|....::|.::    ||..
  Rat     4 FAQVMAEVGDFGPFQVRVTILMGIPNFLSAFFVFSQVFMVLDEAHHCSVSWVKNHTFNLSAAEQL 68

  Fly    66 AIYAP---FKRP-SCTRL------ASINMDGSNATASSEPCNR-WIYHYDHGFISMNADLNWVCD 119
            |:..|   ..|| ||...      ||:....|:....::.|:. |.|. ::...|:..:.:.||:
  Rat    69 AVSIPNDTAGRPESCLMFRPPPDSASLEDILSHRFNETQACDSGWDYP-ENRPPSLKNEFDLVCE 132

  Fly   120 DAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFV 184
            .....|..||:|..|.:.|.|:||.:.|.|||..:::|......:...||.|..:...:....|.
  Rat   133 RENLKRTSQSVFMAGLLVGALVFGPVCDWIGRRASILLQVLLSGITGVATAFVPSFELYMVLCFF 197

  Fly   185 SGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQ 249
            |.:|.........|||.|:|.|:.|:..:.|....| .||::..:.....:.:||...:....|.
  Rat   198 SAIAVAGYMMSTMILVSEWVGPSWRTRAMVLAQSNF-ALGLMALAGLAYGVRNWRLLQIIGTTPI 261

  Fly   250 LLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEARSQMS 314
            .|:..:::::.||.:||:::...:.|:..:::.|..|.|.::               ||..:|:.
  Rat   262 FLLVFYFWVLPESPRWLLSQGRTEEAKQLVQKAALVNGRPLA---------------SELLNQLV 311

  Fly   315 MQK---QARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLPPS 376
            .:|   ....:|.|:.|:||...:.:..|:.:.:|.|..:...|....:..::...:|.:...|:
  Rat   312 PEKTGPSGNALDLFRHPQLRKVTLILIAVWFVDSLLYYGLGFQVGDFGLDIYLTQVIFGVVEVPA 376

  Fly   377 GIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTM 441
            .:....:.:..|||::.:.::|..|:|.    :::.|......||...|.::.:|..|.....:.
  Rat   377 RLSSIPMMEKLGRKWSQLCTLTLAGVMC----VIIIFIPGDLPTVATALAVVGKFASSAAFTISY 437

  Fly   442 QISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAWICLLLSET 506
            ..:.||:||.:|.:|:.::.:.:.....|:|.::.|:.|.:|...:|...|.:.:..:|.||.||
  Rat   438 VYTAELLPTIIRQTGMGLVSIFSRVGGIITPLVMLLEQYHKAIPMLIFGSLPIGAGLLCALLPET 502

  Fly   507 RNKKLPLTLAEGEEFG 522
            |.:.|..||.:.|:.|
  Rat   503 RGQTLKDTLQDLEQGG 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	118/518 (23%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	82/376 (22%)
LOC685081	XP_008764922.2	2A0119	12..510	CDD:273328	118/518 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347208
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950