Protein Alignment CG14856 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 664
• Identity: 145/664 - (21%)
• Similarity: 254/664 - (38%)
• Gaps: 175/664 - (26%)

  Fly     1 MAMDFDEILVKC--GDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCY----HEQLENR 59
            :.:|:|..::..  |....||..|:.|..:....:....|:.:.:...|:.||:    ..:|...
  Rat    76 LLLDYDGSVLPFLGGLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGA 140

  Fly    60 S----YAEIAAIYAPFKRPSCTRLASINMDGSNATASSEP----------------CNRWIYHYD 104
            :    :.::....:|...|..|  ||.....:.:.:|..|                |:.|.|...
  Rat   141 TVTGRWGDMGNWTSPSATPFST--ASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCECHAWDYGIR 203

  Fly   105 HGFISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDS 167
            .|.: .|....|  |||:|:|..|.:....||.:.|.|:.|.:.|.:|| :.|:|.:....|...
  Rat   204 TGLV-QNVVSKWDLVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGR-RPVLLFSVIFILIFG 266

  Fly   168 ATIFAETLLT-FSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFY---------- 221
            .|:.....:| ||..||..|.........::.|.:|...|..|.:   :||...:
  Rat   267 LTVALSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFI---ITMVASFVAMAGQFLMP 328

  Fly   222 GLGMICASWQGVWLGSWRSFMVWTAL---PQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVA 283
            ||..:|..||           |..||   |.||:..::.:..||.:||:..|.|:.|:..:
  Rat   329 GLAALCRDWQ-----------VLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLI---- 378

  Fly   284 KFNRRDVSEADYELFRQHCKTKESEARSQM-SMQKQARLIDSFKLPRLRLRLIYVTVV------F 341
                       ..|.:::|.:.||:.:..| .::|:        |.|...::..|.||      .
  Rat   379 -----------LYLTQKNCVSPESDIKGVMPELEKE--------LSRRPKKVCIVKVVGTRNLWK 424

  Fly   342 SIVTLCYNTM---------SRNVEGLSIS-PFV------MFSLFALTLPPSGIFQTQVQKHFGRK 390
            :||.||.|::         :|::.|..:. |.:      .:::.::.| .|.:....|.:..||:
  Rat   425 NIVVLCVNSLTGYGIHHCFARSMMGHEVKVPLLENFYADYYTMASIAL-ASCLAMCLVVRFLGRR 488

  Fly   391 --------FTSVVSMTATGLMTATTGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQIS--- 444
                    .|::.|:...||:.     |:..::||..:.   |.|....|:|.:......|:
  Rat   489 GGLLLFMILTALASLLQLGLLN-----LIGKYSQHPDSE---LQLKLAVGMSDSVKDKFSIAFSI 545

  Fly   445 -----------------TELMPTCVRSSGLAVIHVTAAALSFISPFI-LHLDT-YFRAASSIITC 490
                             .|:.||.:|..||.::..:|......:|.| ||... ||........|
  Rat   546 VGMFASHAVGSLSVFFCAEITPTVIRCGGLGLVLASAGFGMLTAPIIELHNQKGYFLHHIIFACC 610

  Fly   491 ILLLVSAWIC-LLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQ--------------- 539
            .|:.:   || |||.|:|::.||..:|.||.:.:..     :.|.||.:|
  Rat   611 TLICI---ICILLLPESRDQNLPENIANGEHYTRQP-----LLSHKKGEQPLLLTNAELKDYSGL 667

  Fly   540 HDLSADTIEKLMGD 553
            ||::|      :||
  Rat   668 HDVAA------VGD 675

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	131/594 (22%)
		MFS	129..503	CDD:119392	96/441 (22%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		5/27 (19%)
		MFS_SLC22A23	187..608	CDD:341002	103/468 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346865
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.030