DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and oatx

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_017208528.1	Gene:	oatx / 555218	ZFINID:	ZDB-GENE-070115-1	Length:	567	Species:	Danio rerio

Alignment Length:	596	Identity:	137/596 - (22%)
Similarity:	241/596 - (40%)	Gaps:	95/596 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 MDFDEILVKCGDSHRYQYM---LLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLE---NRSY 61
            |.|.::|.:.|...|:|.:   ||::.||||   :......|....||:|.|....:.   |.|.
Zfish     1 MGFADLLDEVGGFGRFQMIHVTLLSIPGLLM---ASQNLLNNFTAGVPEHHCRIPNVTTAMNDST 62

  Fly    62 AEIAAIYAPFKR----PSCTR-------LASINMDGSNAT-ASSEPC-NRWIYHYDHGFISMNAD 113
            ..:...:.|...    ..|:|       |.:..:...||| ..:|.| :.|.|.......|:.::
Zfish    63 TTLLRAFIPLDSSLTLSKCSRYKDTQWHLITDKLSHGNATELQTEGCADGWTYDKSEFISSIVSE 127

  Fly   114 LNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANC--CGFLGDSATIFAETLL 176
            .:.||......::.|:::..|.:.|.::||.|.||.|| ||:::.:.  ...|| |.|..|.:.:
Zfish   128 WDLVCTLRPLKQMSQTIYMGGVLTGAIIFGGLSDRFGR-KALLIWSYFQLALLG-SFTALAPSYV 190

  Fly   177 TFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSF 241
            .:...||::|::..........|.:|:: ||.....:......|:..|.:..:.....|..||..
Zfish   191 VYCIFRFLTGMSVSGVILNAVSLKVEWI-PTKTRTLVGTLSSFFFTFGQMVLAGVAYSLRDWRKI 254

  Fly   242 MVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFN-RRDVSEADYELFRQHCKTK 305
            .:...||..:...:.:...|||:|||.....:.|...|.||||.| :.:::|          |..
Zfish   255 QMAVCLPFFIFFMYSWWFSESARWLVLNGRSEEALKLLHRVAKINGKPEMTE----------KIT 309

  Fly   306 ESEARSQMSMQKQA-----RLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVM 365
            ..|..|.|..:.|:     .:.|..:.|.:|...:.:.||:...:..|..::.:::...::.::|
Zfish   310 LEELESHMQKEVQSSKSIYTVFDLLRTPTMRKISMCLMVVWFSTSFAYYGLAMDLQKFGVNIYLM 374

  Fly   366 FSLFALTLPPSGIFQTQVQKHFGRKFT---------SVV----------SMTATGLMTATTGILL 411
            ..:|.....|:.:....:....||:.|         |::          .:|.|.|.....|...
Zfish   375 QVIFGAVDFPAKLVALLMLSFLGRRLTQGACLLVSASIIFANIFVPEDMQVTRTALAVLGKGFTS 439

  Fly   412 AFWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILH 476
            |.:|        |:.|.        ||       ||.||.:|.:|:..:...:...|..:|.:|.
Zfish   440 ASFT--------CVYLF--------TG-------ELYPTVIRQTGMGFVSTMSRIGSMAAPAVLI 481

  Fly   477 LDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHD 541
            ||....|..||:.....:::..|..||.||.|..||.|:.:.||  |.|:        |.....|
Zfish   482 LDDILPALPSIVYGGSAVIAGLIAFLLPETLNIPLPDTIDDVEE--KWEK--------KNNTAED 536

  Fly   542 LSADTIEKLMG 552
            |:...::::.|
Zfish   537 LALQDVKQVGG 547

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	125/546 (23%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	87/400 (22%)
oatx	XP_017208528.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	4.020