Protein Alignment CG14856 and Slc22a15

DIOPT Version :10

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001101177.1
• Gene: Slc22a15 / 310732
• RGDID: 1311184
• Length: 548
• Species: Rattus norvegicus
• Alignment Length: 575
• Identity: 129/575 - (22%)
• Similarity: 224/575 - (38%)
• Gaps: 89/575 - (15%)

  Fly     3 MDFDEILVKCGDSHRYQ-YMLLALYGLLMFIVSRHYFAQNVIGFVPD-HWCYHEQLENRSYAEIA 65
            |:.:|.....|:...|| |:...|..||...|:.......:||..|. ||...|.|.|:|::
  Rat     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMAELLPNQSHS--- 62

  Fly    66 AIYAPFKRPSCTRLASINMDGSNATASSEPCNRWI-----------YHYDHGFISMNADLNWVCD 119
                                 :.::...:....|:           .|:.:.|.|:.::...:.:
  Rat    63 ---------------------NQSSGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIAN 106

  Fly   120 DAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFV 184
            .:||.....|.||.|...|.:.||.|.||.||.|..:.......|...|..|:.:...|:.:||:
  Rat   107 RSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVTRFL 171

  Fly   185 SGLAAEANSYLMFILVLEYVSPT----MRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWT 245
            .|:.....|.:.|:|:.|.|...    ..|:|     .:|:.:|:...:..|.::.|||:..:..
  Rat   172 VGMMNGGMSLVAFVLLNECVGAAYWALAGSIG-----GLFFAVGIAQYALLGYFIRSWRTLAILV 231

  Fly   246 ALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEAR 310
            .|...:|......|.||.:||.::.....||..|..:||.||:  .:..:.|...
  Rat   232 NLQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNRK--LKCTFSLTHP---------- 284

  Fly   311 SQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLPP 375
            :..|.::....:|.|:...|....:.:..::.:.:|.|..::.:...|..|.:...:|..|...|
  Rat   285 ANRSYRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIP 349

  Fly   376 S---GIFQTQVQKHFGRKFTSVVSMTATGLM---------TATTGILLAFWTQHSATVMVCLLLM 428
            |   .|:... |:.||||.|....:...||.         ...||: .|....||.:::..|.:.
  Rat   350 SYPLCIYLIN-QRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGV-FAVVNSHSLSLLGKLTIS 412

  Fly   429 CRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILL 493
            ..|.|      ....::||.||.:|:.||....:.:.....|:||:..|.....:...|:.....
  Rat   413 AAFNI------VYIYTSELYPTVIRNVGLGTCSMFSRVGGIIAPFVPSLKDVQWSLPFIVFGATG 471

  Fly   494 LVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADTIE 548
            |.|..:.|||.||.|..|..|.::.:           |.|:::..:..||..|::
  Rat   472 LTSGLLSLLLPETLNSPLLETFSDLQ-----------MYSYRRLGEEALSLQTLD 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	121/529 (23%)
Slc22a15	NP_001101177.1	MFS_SLC22A15	71..469	CDD:340935	95/422 (23%)