Protein Alignment CG14856 and Slc22a22

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001013969.1
• Gene: Slc22a22 / 299944
• RGDID: 1304605
• Length: 555
• Species: Rattus norvegicus
• Alignment Length: 585
• Identity: 139/585 - (23%)
• Similarity: 219/585 - (37%)
• Gaps: 120/585 - (20%)

  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAAI 67
            |.|||||...||..|:|..::.:..:|..:.|.|...:|....:|.|.|....|:. |.:||:..
  Rat     1 MAFDEILHHVGDRGRFQIWMIVVLNILSMVSSLHDVIENFTAAIPAHHCSVNLLDT-SRSEISMA 64

  Fly    68 --------------YAPFKRP-SCTR-------LASINMDGSNAT-ASSEPC-NRWIYHYDHGFI 108
                          ..|.::| .|.|       ....|:..||:| ..:||| :.|.  |||...
  Rat    65 MNLTTEAMMKVSIPMGPNQKPEQCRRFRHPQWQFIDSNISTSNSTELETEPCLDGWT--YDHSVF 127

  Fly   109 SMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR--------IKAVVLANCCGF 163
            :......|  |||........|:....|........|::.||.||        :...:|..||.|
  Rat   128 TSTIVTEWDLVCDFQSFKYYAQATSLAGHFVAAPFCGIISDRFGRKPLLMYCSLAYGILGTCCAF 192

  Fly   164 LGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGL----G 224
            :.:.:        .:...||:|..:|........|||||..     ||..:.|:.|..||    |
  Rat   193 VPNFS--------LYCVLRFLSSASASTVGMNCLILVLEET-----SVQWHATVIVLSGLFSSTG 244

  Fly   225 MICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFN-RR 288
            :.........|..|....:.:|||..:....:..:.|||:||:.....|.|...|:|:|..| ::
  Rat   245 LAGLGGLAYVLSDWHLIQLTSALPYFIFFILFCWVPESARWLMITGKTDQALKELQRIASINGKK 309

  Fly   289 DVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSR 353
            |:::   .|..:..::|..|  ...|..|...:.|....|.:|.           :.|||:
  Rat   310 DIAQ---NLTTEDLRSKVKE--DVCSTVKHFSIKDIIINPMIRK-----------IVLCYS---- 354

  Fly   354 NVEGLSISPFVMFSLFALTLP----PSGIFQTQVQKHFGRKFTSVVSMTATG------------- 401
                 |:....:||:|.|.|.    ...||.||:       ...|:.:.:..
  Rat   355 -----SVLFAELFSIFGLLLDVHMLGKNIFVTQI-------LLGVIDIPSKSLTYFILRNVRRRP 407

  Fly   402 ----LMTATTG-ILLAFWTQHSATVMVCLLLMCRFG-----ISVTTGSTMQISTELMPTCVRSSG 456
                |:.||.| |.:..:......|:...:.:...|     ||:.|.    ...||.|..:||:
  Rat   408 LIAFLLFATGGCITITMFLSEDMYVLRLAIFILGKGCFAAFISINTA----YCNELSPVPLRST- 467

  Fly   457 LAVIHVTAAAL-SFISPFILHLDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEE 520
            |..|:::.|.| |.:|...|....||.....|...:|.:|:......|.||.|..:..|:.:.|:
  Rat   468 LNGIYISVARLASVLSALTLVTRKYFVLLPMIFCGVLPIVATINIYFLPETFNHPITDTIKDMEK 532

  Fly   521  520
              Rat   533  532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	131/567 (23%)
		MFS	129..503	CDD:119392	92/414 (22%)
Slc22a22	NP_001013969.1	2A0119	11..526	CDD:273328	131/567 (23%)
		MFS	127..516	CDD:119392	97/438 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347416
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.030