Protein Alignment CG14856 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_113772.1
• Gene: Slc22a2 / 29503
• RGDID: 61936
• Length: 593
• Species: Rattus norvegicus
• Alignment Length: 592
• Identity: 135/592 - (22%)
• Similarity: 235/592 - (39%)
• Gaps: 107/592 - (18%)

  Fly     6 DEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYH---EQLENR---SYAEI 64
            |:||...|:.|.:|.....|..||....:..|.....:||.|||.|:.   .:|..|   |.||.
  Rat     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPDHHCWSPGAAKLSQRCGWSQAEE 69

  Fly    65 AAIYAPFKRPS--------CTR---------------LASINMDGSNATASSEPCNR-WIYHYDH 105
            .....|...||        |.|               |:|:..|.:.....  ||.. |:|:...
  Rat    70 LNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLAADRNQLPLG--PCEHGWVYNTPG 132

  Fly   106 GFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR---IKAVVLANCCGFLGDS 167
            .  |:..:.|.||..::...:.||:..||...|.::.|.|.||.||   :...:|.|..     |
  Rat   133 S--SIVTEFNLVCAHSWMLDLFQSVVNVGFFIGAMMIGYLADRFGRKFCLLVTILINAI-----S 190

  Fly   168 ATIFAET-----LLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMR-------SVGLNLTMCVF 220
            ..:.|.:     :|.|   ||:.||.::|...:.:||:.|:|....|       .:...:.:.:.
  Rat   191 GALMAISPNYAWMLVF---RFLQGLVSKAGWLIGYILITEFVGLGYRRMVGICYQIAFTVGLLIL 252

  Fly   221 YGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKF 285
            .|:..:..:|:      |..|.|  .||......:::.|.||.:||:::.....|...::.:||.
  Rat   253 AGVAYVIPNWR------WLQFAV--TLPNFCFLLYFWCIPESPRWLISQNKIVKAMKIIKHIAKK 309

  Fly   286 NRRDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNT 350
            |.:.|..:...|      |.:.:|..::    :..::|..:.|::|...:         .|.||.
  Rat   310 NGKSVPVSLQNL------TPDEDAGKKL----KPSILDLVRTPQIRKHTL---------ILMYNW 355

  Fly   351 MSRNV--EGLSI-------SPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTAT 406
            .:.:|  :||.:       :.::.|...||...|:...........||::...||....| ....
  Rat   356 FTSSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRVGRRYPWAVSNMVAG-AACL 419

  Fly   407 TGILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFIS 471
            ..:.:....|.....:.||   .|.||::.......::.||.||.:|:.|:.|..........|:
  Rat   420 ASVFIPDDLQWLKITIACL---GRMGITMAYEMVCLVNAELYPTYIRNLGVLVCSSMCDIGGIIT 481

  Fly   472 PFILH-LDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFK 535
            ||::: |...:.....::..::.||:..:.|||.||:.|.||.|:.:.|         :..|..|
  Rat   482 PFLVYRLTDIWMEFPLVVFAVVGLVAGALVLLLPETKGKALPETIEDAE---------NMQRPRK 537

  Fly   536 KADQHDL 542
            |..:.:|
  Rat   538 KERKENL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	126/555 (23%)
		MFS	129..503	CDD:119392	84/398 (21%)
Slc22a2	NP_113772.1	2A0119	12..525	CDD:273328	126/555 (23%)
		MFS	125..492	CDD:119392	88/407 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347251
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950