Protein Alignment CG14856 and Slc22a1

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_036829.1
• Gene: Slc22a1 / 24904
• RGDID: 3224
• Length: 556
• Species: Rattus norvegicus
• Alignment Length: 558
• Identity: 128/558 - (22%)
• Similarity: 229/558 - (41%)
• Gaps: 68/558 - (12%)

  Fly     6 DEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYH---EQLENR---SYAEI 64
            |::|.:.|:...:|.....|..|:...::..|.....:||.|.|:|.:   .:|..|   |.||.
  Rat     5 DDVLEQVGEFGWFQKQAFLLLCLISASLAPIYVGIVFLGFTPGHYCQNPGVAELSQRCGWSQAEE 69

  Fly    65 AAIYAPFKRPS--------CTR---------------LASINMDGSNATASSEPCNR-WIYHYDH 105
            .....|...||        |.|               |:|:..:.|.....  ||.. |:  ||.
  Rat    70 LNYTVPGLGPSDEASFLSQCMRYEVDWNQSTLDCVDPLSSLVANRSQLPLG--PCEHGWV--YDT 130

  Fly   106 GFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR----IKAVVLANCCGFLGD 166
            ...|:..:.|.||.||:|..:.||...:|...|:|:.|.:.||.||    :...::.:..|.|..
  Rat   131 PGSSIVTEFNLVCGDAWKVDLFQSCVNLGFFLGSLVVGYIADRFGRKLCLLVTTLVTSVSGVLTA 195

  Fly   167 SATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGL----GMIC 227
            .|..:...||    .|.:.|:.::.:....:.|:.|:|..     |...|..:.|.:    |::.
  Rat   196 VAPDYTSMLL----FRLLQGMVSKGSWVSGYTLITEFVGS-----GYRRTTAILYQMAFTVGLVG 251

  Fly   228 ASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSE 292
            .:.....:..||...:..:||..|...:|:.:.||.:||::::....|...:.::|:.|.: |..
  Rat   252 LAGVAYAIPDWRWLQLAVSLPTFLFLLYYWFVPESPRWLLSQKRTTRAVRIMEQIAQKNGK-VPP 315

  Fly   293 ADYELFRQHCKTKE-SEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVE 356
            ||.::.   |..:: ||.||       ....|.|:.|.||...:.:..::....:.|..:..:|.
  Rat   316 ADLKML---CLEEDASEKRS-------PSFADLFRTPNLRKHTVILMYLWFSCAVLYQGLIMHVG 370

  Fly   357 GLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATV 421
            ....:.::.|...:|...|:...........||    :..:.|:.|:|....:|:.|.......:
  Rat   371 ATGANLYLDFFYSSLVEFPAAFIILVTIDRIGR----IYPIAASNLVTGAACLLMIFIPHELHWL 431

  Fly   422 MVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPF-ILHLDTYFRAAS 485
            .|.|..:.|.|.::.......::.||.||.:|:.|:.|...........:|| :..|...::|..
  Rat   432 NVTLACLGRMGATIVLQMVCLVNAELYPTFIRNLGMMVCSALCDLGGIFTPFMVFRLMEVWQALP 496

  Fly   486 SIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGK 523
            .|:..:|.|.:..:.|||.||:...||.|:.|.|..|:
  Rat   497 LILFGVLGLTAGAMTLLLPETKGVALPETIEEAENLGR 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	122/540 (23%)
		MFS	129..503	CDD:119392	80/383 (21%)
Slc22a1	NP_036829.1	2A0119	12..525	CDD:273328	122/540 (23%)
		MFS	125..515	CDD:119392	92/415 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166347305
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950