Protein Alignment CG14856 and Slc22a15

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001034460.2
• Gene: Slc22a15 / 242126
• MGIID: 3607704
• Length: 544
• Species: Mus musculus
• Alignment Length: 576
• Identity: 133/576 - (23%)
• Similarity: 222/576 - (38%)
• Gaps: 91/576 - (15%)

  Fly     3 MDFDEILVKCGDSHRYQ-YMLLALYGLLMFIVSRHYFAQNVIGFVPD-HWCYHEQLENRSYAEIA 65
            |:.:|.....|:...|| |:...|..||...|:.......:||..|. ||...:.|.|:|:
Mouse     1 MEVEEAFQAVGEMGLYQMYLCFLLAVLLQLYVATEAILIALIGATPAYHWDMADLLPNQSH---- 61

  Fly    66 AIYAPFKRPSCTRLASINMDGSNAT-ASSEPCNRWI-----------YHYDHGFISMNADLNWVC 118
                                 ||.| ...:....|:           .|:.:.|.|:.::...:.
Mouse    62 ---------------------SNQTLGKGQAFGDWLLTANGSEIHKHVHFSNSFTSIASEWFLIA 105

  Fly   119 DDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRF 183
            :.:||.....|.||.|...|.:.||.|.||.||.|..:.......|...|..|:.:...|:.:||
Mouse   106 NRSYKVSAASSSFFSGVFVGVISFGQLSDRFGRRKVYLTGFALDILFAVANGFSPSYEFFAVTRF 170

  Fly   184 VSGLAAEANSYLMFILVLEYVSPT----MRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVW 244
            :.|:.....|.:.|:|:.|.|...    ..|:|     .:|:.:|:...:..|.::.|||:..|.
Mouse   171 LVGMMNGGMSLVAFVLLNECVGTAYWALAGSIG-----GLFFAVGIAQYALLGYFIRSWRTLAVL 230

  Fly   245 TALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEA 309
            ..|...||......|.||.:||.::.....||..|..:||.||:  .:..:.|...
Mouse   231 VNLQGTLVFLLSLFIPESPRWLYSQGRLSEAEEALYFIAKRNRK--LKCTFSLTHP--------- 284

  Fly   310 RSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSLFALTLP 374
             :..|.:.....:|.|:...|....:.:..::.:.:|.|..::.:...|..|.:...:|..|...
Mouse   285 -ANRSYRATGSFLDLFRYRILLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEI 348

  Fly   375 PS---GIFQTQVQKHFGRKFTSVVSMTATGLM---------TATTGILLAFWTQHSATVMVCLLL 427
            ||   .|:... |:.||||.|....:...||.         ...||: .|....||.:::..|.:
Mouse   349 PSYPLCIYLIN-QRWFGRKRTLAAFLCLGGLACLIVMFLPEKKDTGV-FAVVNSHSLSLLGKLTI 411

  Fly   428 MCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCIL 492
            ...|.|      ....::||.||.:|:.||....:.:.....|:||:..|.....:...|:....
Mouse   412 SAAFNI------VYIYTSELYPTVIRNVGLGACSMFSRVGGIIAPFVPSLKEVQWSLPFIVFGAT 470

  Fly   493 LLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADTIE 548
            .|.|..:.|||.||.|..|..|.::.:           |.|:::..:..||..|::
Mouse   471 GLTSGLLSLLLPETLNSPLLETFSDLQ-----------MYSYRRLGEEALSLQTLD 515

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	125/530 (24%)
		MFS	129..503	CDD:119392	94/389 (24%)
Slc22a15	NP_001034460.2	MFS	121..469	CDD:119392	88/372 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	513..544		1/3 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843798
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940