Protein Alignment CG14856 and Slc22a19

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_659034.1
• Gene: Slc22a19 / 207151
• MGIID: 2442751
• Length: 551
• Species: Mus musculus
• Alignment Length: 587
• Identity: 129/587 - (21%)
• Similarity: 245/587 - (41%)
• Gaps: 78/587 - (13%)

  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLEN--------- 58
            |.|.:::::.|...|:|.:.:....:...:.:.|...:|....:|.|.|:...|:|
Mouse     1 MAFQDLIIQIGSLGRFQILHMIFVLICHALSAPHTLLENFTAAIPSHRCWVPILDNDTASDNGSR 65

  Fly    59 -RSYAEIAAIYAPFK---RP-SCTRLAS-----INMDGSNATAS---SEPC-NRWIYHYDHGFIS 109
             .|..::..|..|..   || .|.|...     ::::|:..|.:   :||| :.|:  ||.....
Mouse    66 ILSQDDLLRISIPLDSNLRPDKCRRYIQPQWHLLHLNGTFPTVTEPDTEPCVDGWV--YDQSTFL 128

  Fly   110 MNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR--------IKAVVLANCCGFL 164
            ......|  ||.......|.:.::..|...|.::.|.|.|:.||        :|..:...|
Mouse   129 STTVTQWDLVCGSQALNSVAKFIYMTGIFIGYIMGGHLSDKFGRKLIFTCSLLKMAITETC---- 189

  Fly   165 GDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFY---GLGMI 226
                ..||.:.|.:.:.||:||:.:........:|:||:.||..::    |.|.:.:   |:|..
Mouse   190 ----VAFAPSFLIYCSLRFLSGIFSSTLRTNSALLILEWTSPKFQA----LVMALIFIASGVGQT 246

  Fly   227 CASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVS 291
            ..........:|....:..::|..|:......:.|||:||:.......:...|::.|..||  :.
Mouse   247 LLGGLAFAFRNWHHLQLALSVPMFLLLIPTRWLSESARWLIMANKPQKSLKELKKAACVNR--IK 309

  Fly   292 EADYELFRQHCKT---KESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSR 353
            .:...|..:..||   :|.||     .|.:...:|.|:.|.||.|:..::.|..:..:....:..
Mouse   310 NSGDALTLEVVKTIMKEELEA-----AQTKPSPLDLFRTPNLRKRICLLSFVRFVSVMSLLGLLI 369

  Fly   354 NVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHS 418
            |::.||.:.|::..|:.:...|:.:.......:.||:.|.::.|:..|:..    :.:.|..|..
Mouse   370 NIQYLSNNVFLLQCLYGVVCIPANVLGNFSMNYMGRRMTQLIFMSVLGISI----LAVVFLPQEM 430

  Fly   419 ATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRA 483
            ..:.|.|..:.....|.:..||:..:.||:||.:|::.|.|:.:..:|...:||.::.|.||..:
Mouse   431 QILRVFLSTLGGAISSASITSTLVHANELVPTIIRATALGVVGIAGSAGGALSPLLMILTTYSAS 495

  Fly   484 ASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQHDLSADTIE 548
            ...||..||..:...:.|||.||:|:.||.::.:.|.              |:....:...|.:.
Mouse   496 LPWIIYGILPFLGGLVALLLPETKNQPLPDSIQDIEN--------------KRKSSKEAKKDVVA 546

  Fly   549 KL 550
            |:
Mouse   547 KV 548

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	123/539 (23%)
		MFS	129..503	CDD:119392	87/387 (22%)
Slc22a19	NP_659034.1	Sugar_tr	11..525	CDD:331684	122/538 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	524..551		5/39 (13%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843976
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940