Protein Alignment CG14856 and Slc22a12

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_033229.3
• Gene: Slc22a12 / 20521
• MGIID: 1195269
• Length: 553
• Species: Mus musculus
• Alignment Length: 588
• Identity: 139/588 - (23%)
• Similarity: 239/588 - (40%)
• Gaps: 96/588 - (16%)

  Fly     3 MDFDEILVKCGDSHRYQ-YMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLEN-RSYAEIA 65
            |.|.|:|.:.|...|:| :..:||...::::.::: ..:|....||.|.|:...|:| .|.|.|.
Mouse     1 MAFPELLDRVGGLGRFQLFQTVALVTPILWVTTQN-MLENFSAAVPHHRCWVPLLDNSTSQASIP 64

  Fly    66 AIYAP---------------------FKRPSCTRLASINMDGSN-ATASSEPC-NRWIYHYDHGF 107
            ....|                     |::|. .:|...|...:| :.|::||| :.|:  |||..
Mouse    65 GDLGPDVLLAVSIPPGPDQQPHQCLRFRQPQ-WQLTESNATATNWSDAATEPCEDGWV--YDHST 126

  Fly   108 ISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATI 170
            ........|  ||:......:.||:|..|.:.|..:.|...||.||.:.:..:.....:..:|..
Mouse   127 FRSTIVTTWDLVCNSQALRPMAQSIFLAGILVGAAVCGHASDRFGRRRVLTWSYLLVSVSGTAAA 191

  Fly   171 FAETLLTFSASRF-----VSGLAAEANSYLMFILVLEYVSP-------TMRSVGLN----LTMCV 219
            |..|...:...||     |:|:.....|.||     |:.|.       |:.::|.:    ||..|
Mouse   192 FMPTFPLYCLFRFLLASAVAGVMMNTASLLM-----EWTSAQGSPLVMTLNALGFSFGQVLTGSV 251

  Fly   220 FYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAK 284
            .||            :.|||...:..:.|..|...:.:.:.|||:||:|....|.....|:|||.
Mouse   252 AYG------------VRSWRMLQLAVSAPFFLFFVYSWWLPESARWLITVGKLDQGLQELQRVAA 304

  Fly   285 FNRRDVSEAD---YELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTL 346
            .|||. :|.|   .|:.|...:.:.|..::..|:   ..|:.:   |.||.|.|...:.:.....
Mouse   305 VNRRK-AEGDTLTMEVLRSAMEEEPSRDKAGASL---GTLLHT---PGLRHRTIISMLCWFAFGF 362

  Fly   347 CYNTMSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILL 411
            .:..::.:::.|..:.|::.:|..:...|.......:....||:...|..:...||.     ||.
Mouse   363 TFYGLALDLQALGSNIFLLQALIGIVDFPVKTGSLLLISRLGRRLCQVSFLVLPGLC-----ILS 422

  Fly   412 AFWTQHSATVMVCLLLMCRFGISVTTGSTMQI---STELMPTCVRSSGLAVIHVTAAALSFISPF 473
            .....|...|:...|.:  .|:....|:...|   |:||.||.:|.:.:.:..|.|...:.:.|.
Mouse   423 NILVPHGMGVLRSALAV--LGLGCLGGAFTCITIFSSELFPTVIRMTAVGLCQVAARGGAMLGPL 485

  Fly   474 ILHLDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKAD 538
            :..|..|......::..::.::|....|||.||:|..||.|:.:.::           :|.||.
Mouse   486 VRLLGVYGSWMPLLVYGVVPVLSGLAALLLPETKNLPLPDTIQDIQK-----------QSVKKV- 538

  Fly   539 QHD 541
            .||
Mouse   539 THD 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	129/549 (23%)
		MFS	129..503	CDD:119392	89/395 (23%)
Slc22a12	NP_033229.3	2A0119	11..526	CDD:273328	129/549 (23%)
		MFS	147..516	CDD:119392	91/399 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843322
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950