Protein Alignment CG14856 and Slc22a5

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_035526.1
• Gene: Slc22a5 / 20520
• MGIID: 1329012
• Length: 557
• Species: Mus musculus
• Alignment Length: 556
• Identity: 120/556 - (21%)
• Similarity: 222/556 - (39%)
• Gaps: 81/556 - (14%)

  Fly     4 DFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVI--GFVPDHWCYHEQLENRSYAEIAA 66
            |:||:....|:...:|.::..|  |...|:...:...:::  ...|:|.|......|.|
Mouse     3 DYDEVTAFLGEWGPFQRLIFFL--LSASIIPNGFNGMSIVFLAGTPEHRCLVPHTVNLS------ 59

  Fly    67 IYAPFKRPSCTRLASINMDGSNATASSEPCNR--------------------------------- 98
                    |..|..||.::..:.....:.|.|
Mouse    60 --------SAWRNHSIPLETKDGRQVPQKCRRYRLATIANFSELGLEPGRDVDLEQLEQESCLDG 116

  Fly    99 WIYHYDHGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR--IKAVVLANCC 161
            |.|..|....::..:.:.||.|.:||.:..||||||.:.|:.:.|.|.||.||  :..:.:....
Mouse   117 WEYDKDVFLSTIVTEWDLVCKDDWKAPLTTSLFFVGVLMGSFISGQLSDRFGRKNVLFLTMGMQT 181

  Fly   162 GFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMI 226
            ||  ....:|:.....|:....:.|:...:|....|:|..|.:|.::|.:...|.:|:||..|.:
Mouse   182 GF--SFLQVFSVNFEMFTVLFVLVGMGQISNYVAAFVLGTEILSKSIRIIFATLGVCIFYAFGFM 244

  Fly   227 CASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVS 291
            .......::..||..::...:|.:|....::.|.||.:||:::.....||:.:|:.||.|.....
Mouse   245 VLPLFAYFIRDWRMLLLALTVPGVLCGALWWFIPESPRWLISQGRIKEAEVIIRKAAKINGIVAP 309

  Fly   292 EADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVE 356
            ...::         .||.:...|.:.|...|...    :|.|.|.|..:.||:  .:.|:|....
Mouse   310 STIFD---------PSELQDLNSTKPQLHHIYDL----IRTRNIRVITIMSII--LWLTISVGYF 359

  Fly   357 GLSISP-------FVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFW 414
            |||:..       :|...|.|....|:.:....:.::..|::    |::|...:..:..:.:...
Mouse   360 GLSLDTPNLHGDIYVNCFLLAAVEVPAYVLAWLLLQYLPRRY----SISAALFLGGSVLLFMQLV 420

  Fly   415 TQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDT 479
            ......:...|:::.:|||:.........:.||.||.||:.|:.|....:...|.:||:.::|..
Mouse   421 PSELFYLSTALVMVGKFGITSAYSMVYVYTAELYPTVVRNMGVGVSSTASRLGSILSPYFVYLGA 485

  Fly   480 YFRAASSIITCILLLVSAWICLLLSETRNKKLPLTL 515
            |.|....|:...|.:::|.:.|...|:....||.|:
Mouse   486 YDRFLPYILMGSLTILTAILTLFFPESFGVPLPDTI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	116/544 (21%)
		MFS	129..503	CDD:119392	89/382 (23%)
Slc22a5	NP_035526.1	2A0119	12..520	CDD:273328	116/544 (21%)
		MFS	123..510	CDD:119392	94/407 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843867
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.950