Protein Alignment CG14856 and Slc22a2

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_038695.1
• Gene: Slc22a2 / 20518
• MGIID: 1335072
• Length: 553
• Species: Mus musculus
• Alignment Length: 591
• Identity: 135/591 - (22%)
• Similarity: 235/591 - (39%)
• Gaps: 102/591 - (17%)

  Fly     6 DEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYH---EQLENR-------- 59
            |:||...|:.|.:|.....|..||....:..|.....:||.|:|.|..   .:|..|
Mouse     5 DDILEHIGEFHLFQKQTFFLLALLSGAFTPIYVGIVFLGFTPNHHCRSPGVAELSQRCGWSPAEE 69

  Fly    60 ---------SYAEIAAIYAPFKRPSCTR---------------LASINMDGSNATASSEPCNR-W 99
                     |..|::.:      ..|.|               |:|:..:.|:...|  ||.. |
Mouse    70 LNYTVPGLGSAGEVSFL------SQCMRYEVDWNQSTLDCVDPLSSLAANRSHLPLS--PCEHGW 126

  Fly   100 IYHYDHGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGR---IKAVVLANC- 160
            :  ||....|:..:.|.||..::...:.|||..||...|.:..|.|.||.||   :...:|.|.
Mouse   127 V--YDTPGSSIVTEFNLVCAHSWMLDLFQSLVNVGFFIGAVGIGYLADRFGRKFCLLVTILINAI 189

  Fly   161 CGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVS-PTMRSVGLNLTMC--VFYG 222
            .|.|...:..:| .:|.|   ||:.||.::|...:.:||:.|:|. ...|:||:    |  :.:.
Mouse   190 SGVLMAISPNYA-WMLVF---RFLQGLVSKAGWLIGYILITEFVGLGYRRTVGI----CYQIAFT 246

  Fly   223 LGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNR 287
            :|::..:.....|.:||.......||......:::.|.||.:||:::.....|...::.:||.|.
Mouse   247 VGLLILAGVAYALPNWRWLQFAVTLPNFCFLLYFWCIPESPRWLISQNKNAKAMKIIKHIAKKNG 311

  Fly   288 RDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMS 352
            :.|..:...|          .|.....|:.....:|..:.|::|...:         .|.||..:
Mouse   312 KSVPVSLQSL----------TADEDTGMKLNPSFLDLVRTPQIRKHTL---------ILMYNWFT 357

  Fly   353 RNV--EGLSI-------SPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTG 408
            .:|  :||.:       :.::.|...||...|:...........||::...||....| ......
Mouse   358 SSVLYQGLIMHMGLAGDNIYLDFFYSALVEFPAAFIIILTIDRIGRRYPWAVSNMVAG-AACLAS 421

  Fly   409 ILLAFWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPF 473
            :.:....|.....:.||   .|.||::.......::.||.||.:|:..:.|..........::||
Mouse   422 VFIPDDLQWLKITVACL---GRMGITIAYEMVCLVNAELYPTYIRNLAVLVCSSMCDIGGIVTPF 483

  Fly   474 ILH-LDTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEF-----GKGERMFDFMR 532
            ::: |...:.....::..::.||:..:.|||.||:.|.||.|:.:.|:.     .|.:|::   .
Mouse   484 LVYRLTDIWLEFPLVVFAVVGLVAGGLVLLLPETKGKALPETIEDAEKMQRPRKKKEKRIY---L 545

  Fly   533 SFKKAD 538
            ..|||:
Mouse   546 QVKKAE 551

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	125/553 (23%)
		MFS	129..503	CDD:119392	86/390 (22%)
Slc22a2	NP_038695.1	2A0119	12..525	CDD:273328	125/553 (23%)
		MFS	125..492	CDD:119392	91/399 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843826
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950