DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and K09E9.1

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_001368581.1	Gene:	K09E9.1 / 181654	WormBaseID:	WBGene00010724	Length:	518	Species:	Caenorhabditis elegans

Alignment Length:	533	Identity:	116/533 - (21%)
Similarity:	184/533 - (34%)	Gaps:	152/533 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    52 YHE----QLENRSYAEIAA--IYAPFKRPS---CTRLASINMDGSNATASSEPCNRWIYHYDHGF 107
            |:|    .|....|..:||  :...|..||   |        |....|..|     |..:.::.|
Worm    55 YYEIRLLVLTQLGYIPVAAAMLMTAFMEPSPEWC--------DTVRETEQS-----WKLNPNNEF 106

  Fly   108 ISMNADLNWVC--DDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATI 170
            .|::.:..:.|  :......:..||...|::.|:.:.|.|.||:|| |.|       :||....|
Worm   107 YSLSVERGFACQKNSNQTTAMMSSLLMWGALIGSFVCGFLSDRLGR-KPV-------YLGCLLMI 163

  Fly   171 -FAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQ--- 231
             ....|||||             .||.::.:             |.|:.   .:|..|..:.
Worm   164 TIGHILLTFS-------------MYLSWMTI-------------NATLA---AMGFFCGGYMVTN 199

  Fly   232 ----------------GVWLGSWRSFMVWTALPQLLVTGFY-----FLI-------------QES 262
                            .|.|..|...|..|||.......:|     |.|             .||
Worm   200 FVILTEAFELPKSRLLVVSLNGWSVSMAVTALAASYTLNWYAYHTIFAIVGACIAIISLATCSES 264

  Fly   263 AQWLVTR--QDFDGAELRLRRVAKFNRRDVSEADYELFRQH------CKTKESEARSQMSMQKQA 319
            .:||...  |: |..::.|:.....|.||:.|.|..:...|      ..|...|.::..::.|..
Worm   265 CRWLSANGLQN-DAKKIALQITLLNNNRDIEEDDISILSWHEILGFSAPTHTDEKKTWKTLFKST 328

  Fly   320 RLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFVMFSL-FALTLPPS------- 376
            |.:..             |.|     :||:.|:        |..|.|.. |::.:.|.
Worm   329 RFLKP-------------TAV-----MCYSFMA--------SSIVSFGFYFSIDVLPGNRYYNMT 367

  Fly   377 --GI--FQTQVQKHFGRKFTS--VVSMTATGLMTATTGILLA---FWTQHSATVMVCLLLMCRFG 432
              ||  |.......|..:|.:  .:::::.||......::|.   :..|....|::.|.||...|
Worm   368 IMGILKFILGFTPFFLNRFLTKRAIAISSVGLCCLAALMILPIQYYDIQCMRWVIIMLSLMIAAG 432

  Fly   433 ISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTY-FRAASSIITCILLLVS 496
            |..|.......|.||.||.|||....|.:......|.::|.|::|.|: |...::|...:|.:..
Worm   433 IDPTWKINHLYSAELFPTSVRSMARGVCNAGGRLGSVMAPMIVYLRTFGFFIPNAIFAVLLFIQL 497

  Fly   497 AWICLLLSETRNK 509
            ..|.:.|.:..:|
Worm   498 VVIVIFLPDDSDK 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	116/533 (22%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	97/437 (22%)
K09E9.1	NP_001368581.1	MFS	98..505	CDD:421695	101/470 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010