DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and F17C11.12

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_505789.1	Gene:	F17C11.12 / 179514	WormBaseID:	WBGene00008923	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	558	Identity:	119/558 - (21%)
Similarity:	208/558 - (37%)	Gaps:	129/558 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLENRSYAEIAAIYAPFKR 73
            |:|.|   ||..:|.....:.|.                      .||.|......|......|
Worm    36 LLKMG---RYSILLCIFVEVAML----------------------SQLSNTMLMVYAGAAPTIK- 74

  Fly    74 PSCTRLASINMDGSNATASS--EPCNRWIY-------HYDHGFISMNADLNWVCDDAYKARVGQS 129
             ||          .|.|.||  |.|..:.|       .::..|..:......:|:||...::|.|
Worm    75 -SC----------GNMTFSSNEEACLHYSYCKEQKEMTFERQFYGITEQFKLLCEDAKLEKLGTS 128

  Fly   130 LFFVGSMCGTLLFGLLGDRIGRIKAVVLANC-CGFLGDSATIFAE--------TLLTFSASRFVS 185
            :..:|.|.|.::||.:||:.||...::...| |...|..:.:.|:        |:|.|    |..
Worm   129 IQMLGVMLGCVVFGQIGDQYGRKTPMMFCLCMCFIFGIMSALSADFKKFTIFRTILCF----FNG 189

  Fly   186 GLAAEANSYLM---------FILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQGVWLGSWRSF 241
            |.:..:..|::         :|..|...||.:..:|:         |......|..:.|     .
Worm   190 GQSTISVVYMIENIPKRTRGYISTLISYSPNVILLGI---------LAFFFQQWDRLAL-----V 240

  Fly   242 MVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFN----RRDVSEADYELFRQHC 302
            :.:..:|.:::..|   :.||.:||:.:.....|:.....:.||:    .:.::|.:.|.|.::.
Worm   241 ISFLTVPAIIMLAF---LHESPRWLMQKGQISHAKKVFLAIEKFDGVPAAKSLNETELENFLENE 302

  Fly   303 KTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPFV--- 364
            ..|: .|.....:.||......||...:......:...|...||...::..|:..::.|.::
Worm   303 HDKQ-VADGNTEVGKQHSFWHLFKTKEIMTGTFVIAFTFFATTLINYSIMFNLGAVAGSIYMNSI 366

  Fly   365 -------MFSLFALTLPPSGIFQTQVQKHFGRKFT-SVVSMTATGLMTATTGILLAF-WTQHSAT 420
                   .||||      ||:...:.:| |.||.. .:.|:....::.|    ::|| .|..:||
Worm   367 LIGLLRYSFSLF------SGLLDYKFEK-FDRKMCHGICSVVTISIIVA----IIAFCLTDTTAT 420

  Fly   421 VMVCLLLMCRFGISVTTGSTMQ-------ISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLD 478
            ..|    :.|.|:.::...|.|       .|.|||||.:||...:...:.:......:|.:.||:
Worm   421 FSV----LIRIGVLLSCAMTSQAIIVASIASNELMPTAIRSISYSTAQLCSRFGIVFAPHVFHLN 481

  Fly   479 TYFRAASSIITCILLLVSA-----WICLLLSETRNKKL 511
            .|......::...:||...     :...|:.||:||.|
Worm   482 LYTGIDFPVLPYAILLAIGLADFIFFRFLIPETKNKPL 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	117/554 (21%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	87/419 (21%)
F17C11.12	NP_505789.1	2A0119	<109..521	CDD:273328	97/448 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010