Protein Alignment CG14856 and SLC22A31

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 439
• Identity: 110/439 - (25%)
• Similarity: 177/439 - (40%)
• Gaps: 69/439 - (15%)

  Fly   115 NW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLAN---CCGFLGDSATIFAE- 173
            ||  ||.|.:|..:.|....:|.:.|.::.|...||.|| :||.:|:   ..| ||.|..:.|.
Human     8 NWNLVCGDGWKVPLEQVSHLLGWLLGCVILGAGCDRFGR-RAVFVASLVLTTG-LGASEALAASF 70

  Fly   174 -TLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMR---SVGLNLTMCV----FYGLGMICASW 230
             |||..   |.:.|.........:::..||...|..|   |:|..|...|    ..||..:...|
Human    71 PTLLVL---RLLHGGTLAGALLALYLARLELCDPPHRLAFSMGAGLFSVVGTLLLPGLAALVQDW 132

  Fly   231 ---QGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSE 292
               ||  ||:..|.::      ||..||..|..||..||:.......|...|.|.|:.:  .|..
Human   133 RLLQG--LGALMSGLL------LLFWGFPALFPESPCWLLATGQVARARKILWRFAEAS--GVGP 187

  Fly   293 ADYELFRQHCKTKESEARSQMSM----QKQARLIDSFKLPRLR------LRLIYVTVVFSIVTLC 347
            .|..|       :|:...::::|    ..|.|......|.|.|      |.|.:.::|...:...
Human   188 GDSSL-------EENSLATELTMLSARSPQPRYHSPLGLLRTRVTWRNGLILGFSSLVGGGIRAS 245

  Fly   348 Y-NTMSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILL 411
            : .:::..|....:..|:...|.|..|    :|........||:...::....|||    ..:||
Human   246 FRRSLAPQVPTFYLPYFLEAGLEAAAL----VFLLLTADCCGRRPVLLLGTMVTGL----ASLLL 302

  Fly   412 AFWTQH--SATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFI 474
            ....|:  ..||:...:|......:|:..|:: .:.|:.||.:|.:||.::    ....|:....
Human   303 LAGAQYLPGWTVLFLSVLGLLASRAVSALSSL-FAAEVFPTVIRGAGLGLV----LGAGFLGQAA 362

  Fly   475 LHLDTYFRAASSIITCIL---LLVSAWIC-LLLSETRNKKLPLTLAEGE 519
            ..|||........:..::   |.|.|.:| |||.|:|::.||.:|.:.:
Human   363 GPLDTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGLPQSLQDAD 411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	109/432 (25%)
		MFS	129..503	CDD:119392	96/405 (24%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:421695	97/408 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153749
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030