DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG14856 and str-176

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	NP_001294210.1	Gene:	str-176 / 13197055	WormBaseID:	WBGene00006220	Length:	540	Species:	Caenorhabditis elegans

Alignment Length:	487	Identity:	106/487 - (21%)
Similarity:	190/487 - (39%)	Gaps:	85/487 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 CTRLASINMDGSNATASSEPCNRWIYHYDHGFISMNADLNWVCDDAYKARVGQSLFFVGSMCGTL 140
            |..||:..    |.|...||..|      :.|.|:..:.|::|:||.|.:...::...|.:.|..
Worm   101 CHELAAFR----NETNLCEPDLR------YQFKSVQVEFNYICEDAKKVKNTITVQTFGVLVGAA 155

  Fly   141 LFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVS 205
            :||.:.|..||.||::::.....|.:..|.::..|..|...|.::|:.....:.:..:.::|.:.
Worm   156 IFGQVSDTFGRRKALLISTLGNGLFNWITAYSPDLFYFMVWRTLAGVFTGGVTVVQMVFMVENIP 220

  Fly   206 PTMR-----SVGLNLTMCVFYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFLIQESAQW 265
            ...|     |:..:..:.:|..:..:|.        .||:..|..|...:.......:::||.:|
Worm   221 RKDRMWIQNSITWSPNLILFPFVAWLCQ--------DWRTMSVVIAASSIATFLACLILEESPRW 277

  Fly   266 LVTRQDFDGAELRLRRVAKFNRRDVSEADYELFRQHCKTKESEARSQMSMQKQA--RLIDSFKLP 328
            |:.:...:.|...|.|:.|.::......:.:|........|..|||....:|..  .|..::|:
Worm   278 LIQKGRIEEARKSLIRIRKTDKLYDETFEKQLDEVLHVEAEKHARSSKKAKKYTFIHLFCTWKM- 341

  Fly   329 RLRLRLIYVTVVFSIVTLCYNTMSRNVEGLSISPF--------------VMFSLFALTLPPSGIF 379
             :...|.::|.:.....:.|:.| .|:|.||.|.:              :..|:....||
Worm   342 -IAQSLTFITGITCTTFIVYSLM-YNMEKLSGSLYWNLAIMGASRWIINIAVSIADYKLP----- 399

  Fly   380 QTQVQKHFGRKFTSVVSMTAT---GLMTAT------TGILLAFWTQHSATVMVCLLLMCRFGISV 435
                  .||||..:.::|..|   .||.|.      .|.|:|..|  .|.|.:|..|..
Worm   400 ------WFGRKMINQIAMICTLFALLMIAVYLYFGYNGQLIAIGT--VAAVSMCSQLFI------ 450

  Fly   436 TTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIITCILLLVSAW-- 498
               :...:..||.||.||:..::.:...:...|..||.:.:|..|   |..|...:|.....:
Worm   451 ---AKYMMVNELYPTAVRNLAVSAVSTMSRIGSMFSPQLFYLSDY---AEWIPYAVLFSCQLYDF 509

  Fly   499 --ICLLLSETRNKKLPLTLAEGEEFGKGERMF 528
              :.|.|.||:.     .:.|.....|.:|:|
Worm   510 IVLSLFLPETKG-----VILENHLPPKHKRIF 536

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	102/471 (22%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	84/407 (21%)
str-176	NP_001294210.1	2A0119	13..527	CDD:273328	103/476 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162927
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940