Protein Alignment CG14856 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 627
• Identity: 138/627 - (22%)
• Similarity: 232/627 - (37%)
• Gaps: 147/627 - (23%)

  Fly     3 MDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWC-YHEQLENRSYAEI-A 65
            |.|:|:|.:.|....:|...:||..|...::..|:.....:..||.|.| ......|.|:.:: .
Human     1 MGFEELLEQVGGFGPFQLRNVALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAPANFSHQDVWL 65

  Fly    66 AIYAPFKRP-----SCTRLASINMDGSNATASSE--------------PCNR-WIYHYDHG---- 106
            ..:.| :.|     ||.|.| ......|.|...|              ||:: |  .|||.
Human    66 EAHLP-REPDGTLSSCLRFA-YPQALPNTTLGEERQSRGELEDEPATVPCSQGW--EYDHSEFSS 126

  Fly   107 -----------FISMNADLNW-------------------------------------------- 116
                       .|.:..:..|
Human   127 TIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSWRESLGGLLSGM 191

  Fly   117 ----VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLT 177
                ||:.....|...:.||.|.:.|.:.||.|.||.||.:.:::|            :..||
Human   192 EWDLVCEQKGLNRAASTFFFAGVLVGAVAFGYLSDRFGRRRLLLVA------------YVSTL-- 242

  Fly   178 FSASRFVSGLAAEAN-SYLMFILV----------------------LEYVSPTMRSVGLNLTMCV 219
                  |.|||:.|: ||:||.:.                      ||::....|:|. .:....
Human   243 ------VLGLASAASVSYVMFAITRTLTGSALAGFTIIVMPLGEAELEWLDVEHRTVA-GVLSST 300

  Fly   220 FYGLGMICASWQGVWLGSWRSFMVWTALPQLLVTGFYFL--IQESAQWLVTRQDFDGAELRLRRV 282
            |:..|::..:..|..:..||..::...||  ...|...|  :.|||:||:|:.....|...|...
Human   301 FWTGGVMLLALVGYLIRDWRWLLLAVTLP--CAPGILSLWWVPESARWLLTQGHVKEAHRYLLHC 363

  Fly   283 AKFNRRDVSEADYELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLC 347
            |:.|.|.|.|   :.|.|...:|.:...   .:.::...:|.|:.||||...:...||:..|...
Human   364 ARLNGRPVCE---DSFSQEAVSKVAAGE---RVVRRPSYLDLFRTPRLRHISLCCVVVWFGVNFS 422

  Fly   348 YNTMSRNVEGLSISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLA 412
            |..:|.:|.||.::.:....||.....||.:......::.||:.|...::..|.|...|. :|::
Human   423 YYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYAGRRLTQAGTLLGTALAFGTR-LLVS 486

  Fly   413 FWTQHSATVMVCLLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHL 477
            ...:..:||   |.:|.:........:....::||.||.:|.:|:.:..:.......::|....|
Human   487 SDMKSWSTV---LAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGMGLTALVGRLGGSLAPLAALL 548

  Fly   478 DTYFRAASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGE 519
            |..:.:...:....:.|::|...|||.|||..:||.|:.:.|
Human   549 DGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQDVE 590

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	132/610 (22%)
		MFS	129..503	CDD:119392	93/398 (23%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	132/610 (22%)
		MFS	206..563	CDD:119392	90/389 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153778
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.960