Protein Alignment CG14856 and slc22a8

DIOPT Version :10

• Sequence 1: NP_650391.1
• Gene: CG14856 / 41790
• FlyBaseID: FBgn0038261
• Length: 557
• Species: Drosophila melanogaster
• Sequence 2: XP_002937554.2
• Gene: slc22a8 / 100490266
• XenbaseID: XB-GENE-22061134
• Length: 556
• Species: Xenopus tropicalis
• Alignment Length: 655
• Identity: 126/655 - (19%)
• Similarity: 203/655 - (30%)
• Gaps: 243/655 - (37%)

  Fly    26 ISHDSKREMENGVSRS---SLVH------GTQTNPNS---------------DTWYDTDAFLLDQ 66
            ::|.||..::..:.:|   ..:|      ....||..               |.|.|...||
 Frog   384 VNHSSKMTIQKAIKQSFSLGYIHLALCADACAGNPFRDHLKKLNLKVEIQLLDLWQDLQHFL--- 445

  Fly    67 VKEVL--NKLNEGSIDDEIWGKIVIMERCKRVAKAYLRK--------TTVIIDGSE--------- 112
              .||  ||.|..:|...:.|        .|:.:.||.:        .:..|.|.:
 Frog   446 --SVLLNNKKNGNAIFRHLLG--------DRICELYLNEQIGPCLPLKSQTIQGLKELLPSGDVI 500

  Fly   113 ------------------DEF-DGKTLGFNHFENPTR----DDHTKEIRAK-------------- 140
                              ||| |.:...|..|....|    ..|.:|...|
 Frog   501 PWIPKAQKEICKMLSPWYDEFLDEEDYWFLLFTTQNRFISSRQHKREFIGKEENILLYKRIQQSL 565

  Fly   141 -----IADGVILKMDYQGNIKGMARGATPIVCQG-------------------------WKEPRN 175
                 :||  :.:|||    :...:.||..:.||                         :|.|:.
 Frog   566 ELSQALAD--MKEMDY----RQWRKIATEDLKQGGSLQVELTSPVFLTDITKMSFEELCYKNPKM 624

  Fly   176 --NCISDRLVRLHGKLNHGAMEDEKAYKVFDMRKFKHSLERELHDGTPDAR--NLLLKTCMRVAL 236
              ..|||..          .:..|||.|:    .||..:.:|....:...|  :||.:|.:|...
 Frog   625 AIQKISDDY----------KIYCEKAPKI----DFKMEIIKETKTVSRSNRKMSLLKRTLVRKPS 675

  Fly   237 VKDGADMNRTPCWFAIVNLVALDMIKE-------KIPLIKSLLNVYGLPSVTSPSPMSGPDNSGF 294
            ::   ..|.|.   .::|...|:..:|       ||||
 Frog   676 MR---PRNLTE---VLLNTQHLEFFREFLKERKAKIPL--------------------------- 707

  Fly   295 NAQTLTQIIAAAVTQANKGTPTPTRNNNNNNQNLTISPEQLAQ--------IASTISIAQTNTLR 351
              |.||.:...::....|...:...|.........:|||::.|        |||...:..:..|.
 Frog   708 --QFLTAVQKISIETNEKICKSLIENVIKTFFQGQLSPEEMLQCDAPIIKEIASMRHVTTSTLLT 770

  Fly   352 TADLVKKERPKK---------PYHCSTSSLDSSGEDSSGRRSE-ASTAI-KSRAKRW-EQVQKIN 404
            ....|.|...:|         |.|.....:.|..:.||.:.|: .||.: :|:.|.| ..:..|.
 Frog   771 LQGHVMKSIEEKWFKDYQDLFPPHHQEVEVQSEVQISSRKPSKIVSTYLQESQKKGWMRMISFIR 835

  Fly   405 EIEKYTESPAVQMLDKPRAGGRAHRPLLQDVIFTRSHSITSDYDSNKEHF-----DSGSWS--ST 462
            ...||...    ||:..:      |...:|.:.       .:..::||:|     .||..:  ||
 Frog   836 SFCKYRRF----MLNPSK------RQEFEDYLH-------QEMQNSKENFTTAHNTSGRSAPPST 883

  Fly   463 QSRYKDGRSTSSSVVSE----HELAAL--ARDELKETSEIREANAVSEEG----VSPAPRRGDGS 517
            ..|..|..:...::|..    |.:..:  |.::|...||:.:.|.:....    |:.|....|..
 Frog   884 NVRSADQENGEITLVKRRIFGHRIITVNFAINDLYFFSEMEKFNDLVSSAHMLQVNRAYNENDVI 948

  Fly   518 LLRSK 522
            |:|||
 Frog   949 LMRSK 953

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	121/645 (19%)
slc22a8	XP_002937554.2	MFS_SLC22A6_OAT1_like	105..510	CDD:341004	24/138 (17%)