DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14856 and slc22a16

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_002936981.2	Gene:	slc22a16 / 100488673	XenbaseID:	XB-GENE-961385	Length:	567	Species:	Xenopus tropicalis

Alignment Length:	558	Identity:	124/558 - (22%)
Similarity:	227/558 - (40%)	Gaps:	57/558 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 FDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQ------LENRS--- 60
            ||.:    |...|:|.::.............||.|...|...|...|...:      |.|.|
Frog     5 FDYV----GHFGRFQALIYFSSAFQAISCGIHYLASVFIAITPKFICRAPENISSVLLPNASTLR 65

  Fly    61 YAEIAAIYAP---------------------FKRPSCTRLASINMDGSNATASSEPCNRWIYHYD 104
            ..::..::.|                     |||.: |...:.:.||:....|   |:.. |:||
Frog    66 LEDVWELWTPKDYLVVKQENGDIWELNQCSRFKREN-TSYLTYSYDGNKTLFS---CSNG-YYYD 125

  Fly   105 HGFISMNADLNW--VCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDS 167
            :..:..:...:|  ||:..:.|::.|..|..|.:.|.::||.:.||:||...:.|.:...||...
Frog   126 NTNLESSIVTDWHLVCEREWLAKLIQPTFMFGVLIGAVIFGDIADRVGRRLILWLTSTGQFLFGI 190

  Fly   168 ATIFAETLLTFSASRFVSGLAAEANSYLMFILVLEYVSPTMRSVGLNLTMCVFYGLGMICASWQG 232
            |..|.....:|...||:..:.:.....::|:.|.|||....|| ..::.:..|:.:|::..|..|
Frog   191 AVAFTFDYYSFVIVRFLLAMVSSGYYVVVFVYVTEYVGIKARS-WASMHVHAFFAVGVMIVSLVG 254

  Fly   233 VWLGSWRSFMV---WTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRRDVSEAD 294
            ..:.:|..:.:   .|.||.:|..   :::.|:..||.::......|..:..:.|:|:.......
Frog   255 FLVRTWWMYQIILSLTTLPFVLCC---WMLPETPFWLYSQGKHKEVEKLIGTIEKWNKISTPCKL 316

  Fly   295 YELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLS 359
            .||    |..:|:: :::|...|:..::|.|.......|.:.|.:::...:|.|...:.|...|.
Frog   317 SEL----CSVQETQ-KTEMDTLKKHSVLDLFYNWSFARRTVTVWLIWFTGSLGYYVFALNSVNLG 376

  Fly   360 ISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATGLMTATTGILLAFWTQHSATVMVC 424
            .:.::...|.:....||.|.........||:.|....:.   |.....||::.....|| ||.:.
Frog   377 GNEYLNLFLTSAVEIPSYIVACFGMDKIGRRNTLAPFLI---LSAVICGIIMLIPQDHS-TVTIA 437

  Fly   425 LLLMCRFGISVTTGSTMQISTELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFRAASSIIT 489
            :.:..:|.|:|..|.....:.||.||.|||..:....:.....|.::||.::|...:.....::.
Frog   438 MSMGGKFSIAVAFGLIYLYTAELYPTIVRSLAVGSGSMMCRIGSVVAPFCVYLTDVWIFMPQMLV 502

  Fly   490 CILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERM 527
            .|:..::..:.|.|.||....|..|:.|..|.|...|:
Frog   503 GIMAFLTGVLTLKLPETLGVPLTSTIEEAAEMGTNNRI 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	117/535 (22%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	84/376 (22%)
slc22a16	XP_002936981.2	MFS_SLC22A16_CT2	111..517	CDD:340933	95/422 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000