DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14856 and zmp:0000001102

DIOPT Version :9

Sequence 1:	NP_650391.1	Gene:	CG14856 / 41790	FlyBaseID:	FBgn0038261	Length:	557	Species:	Drosophila melanogaster
Sequence 2:	XP_001340340.6	Gene:	zmp:0000001102 / 100000058	ZFINID:	ZDB-GENE-140106-62	Length:	560	Species:	Danio rerio

Alignment Length:	592	Identity:	157/592 - (26%)
Similarity:	259/592 - (43%)	Gaps:	84/592 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAMDFDEILVKCGDSHRYQYMLLALYGLLMFIVSRHYFAQNVIGFVPDHWCYHEQLE-----NRS 60
            :.|.||.||.:.....|||..|:.|..:....:..|:...|.|..:|.|.|....|:     |.:
Zfish     9 VTMKFDNILDETDGFGRYQIALVMLLFIPRITIPCHFLLNNFIAAIPSHHCDISSLDADGLGNLT 73

  Fly    61 YAEIAAIYAPFKR----PSCTRLAS------INMDGSNATASSEPCNRWIYHYDHG-FIS-MNAD 113
            ..|...:..|.:.    .||...|.      ||...|:|....|..|.|  |:|:. ||| :...
Zfish    74 QKERLIVSVPAQEDGTPASCHMFAHPQFQLLINSSSSSALPVVECQNGW--HFDNSTFISTLATQ 136

  Fly   114 LNWVCDDAYKARVGQSLFFVGSMCGTLLFGLLGDRIGRIKAVVLANCCGFLGDSATIFAETLLTF 178
            .:.|||....|:...::||||.|||.:.||:|.|:.||...::::.....:....:.|:.:.:.|
Zfish   137 FDLVCDKRGLAKASATIFFVGVMCGAVFFGVLCDKYGRRSMLLVSYVFSIVFSVTSAFSSSYIMF 201

  Fly   179 SASRFVSGLAAEANSYLMFILVLEYVSPTMRS-VGLNLTMCVFYGLGMICASWQGVWLGSWRSFM 242
            :|.||::|||....|.:..:|.:|:|....|: :||..:|.  :.:|.:..:.....:..||..:
Zfish   202 AAFRFLTGLALTGISNISVVLSIEWVDTKHRTFMGLFGSMS--WSIGNMLLAGFAFMVTDWRLLI 264

  Fly   243 VWTALPQLLVTGFYFLIQESAQWLVTRQDFDGAELRLRRVAKFNRR-------------DVSEAD 294
            |....|..|.|..::.|.:||:||:.....:.|...|.:.|.||:|             .|...|
Zfish   265 VIVTAPLFLATATWWWIPDSARWLIANGKTETAYKYLHKCATFNKRLDFTSRVKPETLSTVVTVD 329

  Fly   295 YELFRQHCKTKESEARSQMSMQKQARLIDSFKLPRLRLRLIYVTVVFSIVTLCYNTMSRNVEGLS 359
            :   |.|..|                .:|..|.|:||...::..:|:..|...|..:|.|:.|..
Zfish   330 H---RGHSYT----------------YLDLVKTPQLRKLTLFTGIVWYGVASTYYGISLNITGFG 375

  Fly   360 ISPFVMFSLFALTLPPSGIFQTQVQKHFGRKFTSVVSMTATG------LMTATTGILLAFWTQHS 418
            :.|::...::|....|:.|.........||:.|...::..||      ::|.|     .:||  .
Zfish   376 LDPYLTHFIYAAIEVPAKILVYFSLNKVGRRNTQTGTLVLTGFCILINIITPT-----EYWT--F 433

  Fly   419 ATVMVCLLLMCRFGISVTTGSTMQI-STELMPTCVRSSGLAVIHVTAAALSFISPFILHLDTYFR 482
            .||:..|    ..|:|..:.:|:.: :|||.||.:|.:||...:..|...:.|||.|:.|:..::
Zfish   434 RTVIAVL----GKGLSEASFTTVILYTTELYPTVMRQNGLGFTNFMARMGASISPLIMLLEDIWK 494

  Fly   483 AASSIITCILLLVSAWICLLLSETRNKKLPLTLAEGEEFGKGERMFDFMRSFKKADQH------D 541
            ....:|.|.:.:....|.|||.||.|..||.|:.:.|:..| :.::     |..|||.      .
Zfish   495 LLPEVIFCSMAIFCGIIALLLPETNNASLPETVEDIEDMRK-KPVY-----FTTADQSAMPLKLP 553

  Fly   542 LSADTIE 548
            |:|||.:
Zfish   554 LTADTTQ 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14856	NP_650391.1	2A0119	13..514	CDD:273328	141/538 (26%)
CG14856	NP_650391.1	MFS	129..503	CDD:119392	100/394 (25%)
zmp:0000001102	XP_001340340.6	Sugar_tr	22..526	CDD:331684	141/537 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D284622at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010