Protein Alignment CG14855 and SLC22A13

DIOPT Version :10

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_004247.2
• Gene: SLC22A13 / 9390
• HGNCID: 8494
• Length: 551
• Species: Homo sapiens
• Alignment Length: 566
• Identity: 146/566 - (25%)
• Similarity: 247/566 - (43%)
• Gaps: 76/566 - (13%)

  Fly     3 FEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSF---AEIEK 64
            |.::||:.|:..|:|..||.|...|..:...::|:...:.....|.|....::|.:|   |..:.
Human     4 FVQVLAEIGDFGRFQIQLLILLCVLNFLSPFYFFAHVFMVLDEPHHCAVAWVKNHTFNLSAAEQL 68

  Fly    65 IYS-------------QFEKPSC-TRLEKIDEDGQNHTLSRERCNR-WIYKYDFGYKSMNTELNW 114
            :.|             .|..|.. ..|:.|.....|.|   :.|:. |.|. :....|:..|.|.
Human    69 VLSVPLDTAGHPEPCLMFRPPPANASLQDILSHRFNET---QPCDMGWEYP-ENRLPSLKNEFNL 129

  Fly   115 VCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGF-LGDFSTIFAGSLTSFSI 178
            |||..:.....||:|..|.:.|||.||.|.||||| :|.|||....| |...:|.|..|...:..
Human   130 VCDRKHLKDTTQSVFMAGLLVGTLMFGPLCDRIGR-KATILAQLLLFTLIGLATAFVPSFELYMA 193

  Fly   179 SRFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSF-YCLGLIGACWLAVWVGHWRIFLAC 242
            .||....|....|:....|:.|:|.||.|...:  ||... :.||.:....||....:||:....
Human   194 LRFAVATAVAGLSFSNVTLLTEWVGPSWRTQAV--VLAQCNFSLGQMVLAGLAYGFRNWRLLQIT 256

  Fly   243 SSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKD 307
            .:.|.||:..:::.:.|||:||:||..:|.||:.:::.|.:|||:::.:       ...|...:.
Human   257 GTAPGLLLFFYFWALPESARWLLTRGRMDEAIQLIQKAASVNRRKLSPE-------LMNQLVPEK 314

  Fly   308 KNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGISPFIMFSLNALTLPPSG 372
            .....:|  ||:.:.|::|.....:..::.:....|..::..|...|:..::...:......|:.
Human   315 TGPSGNA--LDLFRHPQLRKVTLIIFCVWFVDSLGYYGLSLQVGDFGLDVYLTQLIFGAVEVPAR 377

  Fly   373 YLQGLLQDRMGRKATAVGWMAITGIFAVAAGLVISQGSNRNV----LLLVG-LTMAARFGVSIAD 432
            .....:..|.|||.:.:|.:.:.|:..:   ::|...::..|    |.:|| :..||.|.:|..
Human   378 CSSIFMMQRFGRKWSQLGTLVLGGLMCI---IIIFIPADLPVVVTMLAVVGKMATAAAFTISYV- 438

  Fly   433 GASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLL 497
                 :|.||.||.:|..|:.:|.:.......|:|.::.||.|:...|.:|.|.|.:....:|.|
Human   439 -----YSAELFPTILRQTGMGLVGIFSRIGGILTPLVILLGEYHAALPMLIYGSLPIVAGLLCTL 498

  Fly   498 LPETRNKKLPMSLAEGEEFGRGEGIFDFLRHMFRREGSKSEVEMGP 543
            ||||                .|:|:.|.|:          ::|:||
Human   499 LPET----------------HGQGLKDTLQ----------DLELGP 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	136/520 (26%)
SLC22A13	NP_004247.2	MFS_OAT	102..500	CDD:340932	114/422 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	511..551		4/18 (22%)