Protein Alignment CG14855 and TPO2

DIOPT Version :10

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_011654.1
• Gene: TPO2 / 853039
• SGDID: S000003370
• Length: 614
• Species: Saccharomyces cerevisiae
• Alignment Length: 568
• Identity: 102/568 - (17%)
• Similarity: 183/568 - (32%)
• Gaps: 191/568 - (33%)

  Fly    78 EKIDEDGQNH-----------TLSRERCNRWIYKYDFGYKSMNTELNWVCDEAY----------- 120
            |:.|:.|:|.           |...|..:.|.....:.|..:.:.|  |...||
Yeast   134 EREDQSGENELDPEIEFVTFVTGDPENPHNWPSWVRWSYTVLLSIL--VICVAYGSACISGGLGT 196

  Fly   121 ---KARVGQ-------SLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTS 175
               |..||.       ||..:|...|.|.:..:.|..||..|..::.....:.:.....|.:|..
Yeast   197 VEKKYHVGMEAAILSCSLMVIGFSLGPLIWSPVSDLYGRRVAYFVSMGLYVIFNIPCALAPNLGC 261

  Fly   176 FSISRFISGLAADANSYLM------------------YILILEYVSPSLRNVGLNTVLGSFYCLG 222
            ....||:.|:.:.:...|:                  :.....||.|.     :..::..|..:.
Yeast   262 LLACRFLCGVWSSSGLCLVGGSIADMFPSETRGKAIAFFAFAPYVGPV-----VGPLVNGFISVS 321

  Fly   223 LIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRR------LERVA 281
             .|...|..||.     :|.:.|                .|:::     .||..      |:|.|
Yeast   322 -TGRMDLIFWVN-----MAFAGV----------------MWIIS-----SAIPETYAPVILKRKA 359

  Fly   282 KINRRQVADKDFKDFRIYCEQHYRKDKNQEEHAKLLDMLKT------------PRMRSTAFKLLL 334
            ...|::..:.     :|..||       :.:...:.:|::.            |.:.:|.|.:.|
Yeast   360 ARLRKETGNP-----KIMTEQ-------EAQGVSMSEMMRACLLRPLYFAVTEPVLVATCFYVCL 412

  Fly   335 IFIIIVPCYNTI----------ARNVEGLGISPFIMFSLNALTLP---PSGYLQGLLQ------D 380
            |:.::...:...          ..|:.||...|.::.:|.||...   .:.|||.:.|      |
Yeast   413 IYSLLYAFFFAFPVIFGELYGYKDNLVGLMFIPIVIGALWALATTFYCENKYLQIVKQRKPTPED 477

  Fly   381 R-MGRKATAVGWMAITGIFAVAAGLVISQGSNRNVLLLVGLTMAARFGVSI-------------- 430
            | :|.|        |...||..|..::...:.::::.:...:....||..:
Yeast   478 RLLGAK--------IGAPFAAIALWILGATAYKHIIWVGPASAGLAFGFGMVLIYYSLNNYIIDC 534

  Fly   431 -ADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYV 494
             ...|||..:|::...|..|....:     |.........||.|::.         |.|:|.|.:
Yeast   535 YVQYASSALATKVFLRSAGGAAFPL-----FTIQMYHKLNLHWGSWL---------LAFISTAMI 585

  Fly   495 CLLLPETRNKKLPMSLAEGEEFGRGEGIFDFLRH-MFRREGSKSEVEM 541
            .          ||.:.:   .:|:|      ||| :.:::.|...|||
Yeast   586 A----------LPFAFS---YWGKG------LRHKLSKKDYSIDSVEM 614

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	91/531 (17%)
TPO2	NP_011654.1	MFS_Tpo1_MDR_like	173..599	CDD:340881	87/512 (17%)