Protein Alignment CG14855 and Slc22a16

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_081848.1
• Gene: Slc22a16 / 70840
• MGIID: 1918090
• Length: 649
• Species: Mus musculus
• Alignment Length: 598
• Identity: 140/598 - (23%)
• Similarity: 239/598 - (39%)
• Gaps: 127/598 - (21%)

  Fly     4 EEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYHEQLENRSFAEIEKIYSQ 68
            |.|....|:..|:|.||..:..|..:...:||.|...:|.:|:|.|....:..::.
Mouse     7 ELIFDHIGHFGRFQIVLYLICAYQSLSCGIHYLSSVFLSIIPEHACKPPGMVRKAV--------- 62

  Fly    69 FEKPSCTRLEKI---------D------EDGQNHTLSRERCNR-WI-------YKYDFGYK---- 106
            |...|..|||.|         |      :||:...|:  ||:| |.       |:|. |||
Mouse    63 FHNVSAWRLEDILALRSPEHKDHIMVELQDGEIWELT--RCSRTWRENTSHLGYEYS-GYKHDSP 124

  Fly   107 --------------SMNTELNWVCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILAN 157
                          |.....|.|||:.:.||:.|.|...|.:.|::.|..|.||.||..||
Mouse   125 CFDGYVYDQSKWRNSAVRNFNLVCDQKWYARMIQPLIIFGVMLGSITFSYLSDRFGRRMAL---- 185

  Fly   158 WCGFLGDF----STIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLR---NVGLNTVL 215
            ||..:|.|    :::|.....||.|:||...:|:.....::::.::|.:....|   ::.|||
Mouse   186 WCTSIGVFFFGIASLFIFDYLSFMITRFFLVMASSGYFVVVFVYVMEIIGKKARTWASIHLNT-- 248

  Fly   216 GSFYCLG---------LIGACWLAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVD 271
              |:.:|         |:...||      ::|.|...:.|.:|..   :::.|:..||::.....
Mouse   249 --FFAIGAMLVALASYLLKTWWL------YQIILCIVTTPFILCC---WMLPETPFWLLSEGRYK 302

  Fly   272 GAIRRLERVAKINRRQVAD-KDFKDFRIYCEQHYRKDKNQEEH--AKLLDMLKTPRMRSTAFKLL 333
            .|...::.:|..|:....| .:.....: ...|.:...:..:|  |.|...|...:|  |....|
Mouse   303 EAQGTVDTMAVWNKSSSCDLVELLSLDV-TRSHNKSPHSIRKHRLADLFHNLDVAKM--TLIVWL 364

  Fly   334 LIFIIIVPCY---NTIARNVEGLGISPFIMFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAIT 395
            ..|...:..|   ..:.|..|.   .|..:..:.|:.:|....|...|: |:||:.|.:.::.::
Mouse   365 DWFTANLGYYMFGKEVIRRKEN---EPLYLLLVGAMEIPAYICLCIWLK-RVGRRKTMLLFLLVS 425

  Fly   396 GIFAVAAGLVIS--QGSNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVA 458
            .:..:...::.|  :.:.|.|.|||...:::.|.....      ::.||.||:||...|...::.
Mouse   426 SLTCMLHVVMPSDYKTAKRMVALLVKSVISSVFAFIYL------YTAELYPTTVRCLAVGSSNMV 484

  Fly   459 GFAASFLSPYILHLGTYYKPAPSIILGLLFLSGAYVCLLLPETRNKKLPM--------------- 508
            ...:|...|:..|....:...|.|:.|:|.:....:.|.||||::  .||
Mouse   485 SHVSSIFIPFTSHFSKVWIFLPQILFGILAILSGLLSLKLPETQD--TPMKSTWETTEQQVPENK 547

  Fly   509 -SLAEG--EEFGR 518
             ||.||  :.|.|
Mouse   548 DSLGEGPPDSFER 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	130/560 (23%)
		MFS	127..499	CDD:119392	86/395 (22%)
Slc22a16	NP_081848.1	2A0119	14..535	CDD:273328	132/564 (23%)
		MFS	163..525	CDD:119392	85/391 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	530..560		7/29 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	579..649

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843692
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940