Protein Alignment CG14855 and Slc22a23

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_072146.1
• Gene: Slc22a23 / 64559
• RGDID: 620302
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 591
• Identity: 132/591 - (22%)
• Similarity: 223/591 - (37%)
• Gaps: 122/591 - (20%)

  Fly    11 GNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCY----HEQLENRSFAEIEKIYSQFEK 71
            |....||..|:.|.....:.:....||.:.:...|:.||:    ..:|...:..........:..
  Rat    90 GLGGGYQKTLVVLTWIPALFIGFSQFSDSFLLDQPNFWCHGAGKGTELAGATVTGRWGDMGNWTS 154

  Fly    72 PSCT------------RLEKID------EDGQNHTLSRERCNRWIYKYDFGYKS---MNTELNW- 114
            ||.|            |....|      ..|:.:..|...|:.|    |:|.::   .|....|
  Rat   155 PSATPFSTASWGTTSNRSNSSDTPPLPSPPGKGNNDSNCECHAW----DYGIRTGLVQNVVSKWD 215

  Fly   115 -VCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIF--------- 169
             |||.|:|..|.:....||.:.|.|..|.:.|.:|| |.::|         ||.||
  Rat   216 LVCDNAWKVHVAKFSLLVGLIFGYLITGCIADWVGR-RPVLL---------FSVIFILIFGLTVA 270

  Fly   170 -AGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNV-----GLNTVLGSFYCLGLIGACW 228
             :.::|.||..||..|.........:|.|.:|...|..|.:     ....:.|.|...||...|
  Rat   271 LSVNVTMFSTLRFFEGFCLAGIILTLYALRIELCPPGKRFIITMVASFVAMAGQFLMPGLAALC- 334

  Fly   229 LAVWVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDF 293
                 ..|::..|....|.||:.|::.:..||.:||:.....:.|.:.:..:.:.|... .:.|.
  Rat   335 -----RDWQVLQALIICPFLLMLLYWSIFPESLRWLMATQQFESAKKLILYLTQKNCVS-PESDI 393

  Fly   294 KDFRIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTI---------ARN 349
            |......|      |......|.:.::|....|:      |...|:|.|.|::         ||:
  Rat   394 KGVMPELE------KELSRRPKKVCIVKVVGTRN------LWKNIVVLCVNSLTGYGIHHCFARS 446

  Fly   350 VEGLGIS-PFI------MFSLNALTLPPSGYLQGLLQDRMGRKATAVGWMAITGIFA-VAAGLVI 406
            :.|..:. |.:      .:::.::.| .|.....|:...:||:...:.:|.:|.:.: :..||:.
  Rat   447 MMGHEVKVPLLENFYADYYTMASIAL-ASCLAMCLVVRFLGRRGGLLLFMILTALASLLQLGLLN 510

  Fly   407 SQG-------SNRNVLLLVGLTMAARFGVSIA------------DGASSQFSTELIPTSVRGRGV 452
            ..|       |...:.|.||::.:.:...|||            ...|..|..|:.||.:|..|:
  Rat   511 LIGKYSQHPDSELQLKLAVGMSDSVKDKFSIAFSIVGMFASHAVGSLSVFFCAEITPTVIRCGGL 575

  Fly   453 AVVHVAGFAASFLSPYI-LHLGTYYKPAPSIILGLLFLSGAYVC----LLLPETRNKKLPMSLAE 512
            .:|..:.......:|.| ||....|     .:..::|.....:|    |||||:|::.||.::|.
  Rat   576 GLVLASAGFGMLTAPIIELHNQKGY-----FLHHIIFACCTLICIICILLLPESRDQNLPENIAN 635

  Fly   513 GEEFGR 518
            ||.:.|
  Rat   636 GEHYTR 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	126/578 (22%)
		MFS	127..499	CDD:119392	92/427 (22%)
Slc22a23	NP_072146.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	162..188		3/25 (12%)
		MFS_SLC22A23	187..608	CDD:341002	101/459 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346864
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.030