Protein Alignment CG14855 and SLC22A15

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_060890.2
• Gene: SLC22A15 / 55356
• HGNCID: 20301
• Length: 547
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 132/602 - (21%)
• Similarity: 227/602 - (37%)
• Gaps: 121/602 - (20%)

  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNV----ISFVPD-HWCYHEQLENRSFA 60
            |:.||.....|....||..|..|   |.|::.::..::.:    :...|. ||...|.|.|:|..
Human     1 MEVEEAFQAVGEMGIYQMYLCFL---LAVLLQLYVATEAILIALVGATPSYHWDLAELLPNQSHG 62

  Fly    61 EIEKIYSQFEKPSCTRLEKIDEDGQNHTLSRERCNRW--------IYK---YDFGYKSMNTELNW 114
            .                :...||        :....|        |:|   :...:.|:.:|...
Human    63 N----------------QSAGED--------QAFGDWLLTANGSEIHKHVHFSSSFTSIASEWFL 103

  Fly   115 VCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANWCGFLGDFSTIFAGSLTSFSIS 179
            :.:.:||.....|.||.|...|.::||.|.||.||.:..:.......|...:..|:.|...|:::
Human   104 IANRSYKVSAASSFFFSGVFVGVISFGQLSDRFGRKKVYLTGFALDILFAIANGFSPSYEFFAVT 168

  Fly   180 RFISGLAADANSYLMYILILEYVSPSLRNVGLNTVLGSFYCLGLIGACWLAVWVGHWRIFLACSS 244
            ||:.|:.....|.:.::|:.|.|..:...:. .::.|.|:.:|:.....|..::..||......:
Human   169 RFLVGMMNGGMSLVAFVLLNECVGTAYWALA-GSIGGLFFAVGIAQYALLGYFIRSWRTLAILVN 232

  Fly   245 VPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAKINRRQVADKDFKDFRIYCEQHYRKDKN 309
            :...:|.|....:.||.:||.::..:..|...|..:||.||           ::.|........|
Human   233 LQGTVVFLLSLFIPESPRWLYSQGRLSEAEEALYLIAKRNR-----------KLKCTFSLTHPAN 286

  Fly   310 Q--EEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNTIARNVEGLGISPFIMFSLNALTLPPSG 372
            :  .|....||:.:...:......|:.|:.:....|..:..:...||.|.:...:|:.|...||.
Human   287 RSCRETGSFLDLFRYRVLLGHTLILMFIWFVCSLVYYGLTLSAGDLGGSIYANLALSGLIEIPSY 351

  Fly   373 ----YLQGLLQDRMGRKATAVGWMAI----------------TGIFAVAAGLVISQGSNRNVLLL 417
                ||  :.|...|||.|...::.:                ||:|||.         |.:.|.|
Human   352 PLCIYL--INQKWFGRKRTLSAFLCLGGLACLIVMFLPEKKDTGVFAVV---------NSHSLSL 405

  Fly   418 VG-LTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGTYYKPAPS 481
            :| ||::|.|.:...      :::||.||.:|..|:....:.......::|:|..|.......|.
Human   406 LGKLTISAAFNIVYI------YTSELYPTVIRNVGLGTCSMFSRVGGIIAPFIPSLKYVQWSLPF 464

  Fly   482 IILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGRGEGIFDFLRHMFRREGSKS--------- 537
            |:.|...|:...:.||||||.|..|.            |...|...:.:||.|.::
Human   465 IVFGATGLTSGLLSLLLPETLNSPLL------------ETFSDLQVYSYRRLGEEALSLQALDPQ 517

  Fly   538 -----EVEMGPTIVEED 549
                 |..:|....||:
Human   518 QCVDKESSLGSESEEEE 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	119/534 (22%)
		MFS	127..499	CDD:119392	91/394 (23%)
SLC22A15	NP_060890.2	MFS	111..469	CDD:119392	87/386 (23%)
		MFS_1	111..450	CDD:284993	82/367 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	522..547		4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153620
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.850