Protein Alignment CG14855 and SLC22A17

DIOPT Version :9

• Sequence 1: NP_650390.2
• Gene: CG14855 / 41789
• FlyBaseID: FBgn0038260
• Length: 556
• Species: Drosophila melanogaster
• Sequence 2: NP_065105.3
• Gene: SLC22A17 / 51310
• HGNCID: 23095
• Length: 649
• Species: Homo sapiens
• Alignment Length: 602
• Identity: 154/602 - (25%)
• Similarity: 230/602 - (38%)
• Gaps: 147/602 - (24%)

  Fly     1 MDFEEILAKCGNSSRYQFVLLALYGYLMVVVSMHYFSQNVISFVPDHWCYH----------EQLE 55
            :.||.:||:.|.....|.:.|.|....::.|::...|..:.:..|...|::          ||..
Human    78 LSFEALLAQVGALGGGQQLQLGLCCLPVLFVALGMASDPIFTLAPPLHCHYGAFPPNASGWEQPP 142

  Fly    56 NRSFAEI----------EKIYSQFEKPSCTRLEKIDEDGQNHTLSRERCNRWIYKYDFGYKSMNT 110
            |.|...:          .::.:..: |||:.....|   .||.|     ..|.|.   |...:.|
Human   143 NASGVSVASAALAASAASRVATSTD-PSCSGFAPPD---FNHCL-----KDWDYN---GLPVLTT 195

  Fly   111 EL--NW--VCDEAYKARVGQSLFFVGSVCGTLAFGLLGDRIGRIRALILANW-----CGFLGDFS 166
            ..  .|  |||..::..:.|.||.:|...|.|..|...||.|| |.::|...     ||..|
Human   196 NAIGQWDLVCDLGWQVILEQILFILGFASGYLFLGYPADRFGR-RGIVLLTLGLVGPCGVGG--- 256

  Fly   167 TIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLR-NVGLNTVL----GSFYCLGLIGA 226
             ..|||.|.....||:.|.........:|::.||...|:.| .|.|...|    |.|..||
Human   257 -AAAGSSTGVMALRFLLGFLLAGVDLGVYLMRLELCDPTQRLRVALAGELVGVGGHFLFLG---- 316

  Fly   227 CWLAVWVGHWRIFLACSSVPLLLVTLFY-----FLVQESAQWLVTRNDVDGAIRRLERVAKINRR 286
              ||:....||......:.|.:|. |||     ||  |||:||:.:..::.|...|..:|:.||
Human   317 --LALVSKDWRFLQRMITAPCILF-LFYGWPGLFL--ESARWLIVKRQIEEAQSVLRILAERNR- 375

  Fly   287 QVADKDFKDFRIYCEQHYRKDKNQEEHAKLLDMLKT---PRMRSTAFKLLLIFIIIVPCYNTIAR 348
                            .:.:...:|....|.|:..|   |...|.:|..||       .|..|.:
Human   376 ----------------PHGQMLGEEAQEALQDLENTCPLPATSSFSFASLL-------NYRNIWK 417

  Fly   349 NVEGLGISPFIMFSLNALTLPPSG-------YLQGLLQ---------------DRMGRKATAVGW 391
            |:..||.:.||..::.....|..|       ||..||.               ||.||:...:..
Human   418 NLLILGFTNFIAHAIRHCYQPVGGGGSPSDFYLCSLLASGTAALACVFLGVTVDRFGRRGILLLS 482

  Fly   392 MAITGIFAVAAGLVI----------------SQGSNRNVLLLVGLTMAARFGVSIADGA---SSQ 437
            |.:|||    |.||:                .||:....|....:|..:..|:..:..|   |:.
Human   483 MTLTGI----ASLVLLGLWDCEHPIFPTVWAQQGNPNRDLNEAAITTFSVLGLFSSQAAAILSTL 543

  Fly   438 FSTELIPTSVRGRGVAVVHVAGFAASFLSP-YILHLGTYYKPAPSIILGLLFLSGAYVC----LL 497
            .:.|:|||:|||||:.::...|.......| ..||:|     ..:.:..::..:.|.:|    :|
Human   544 LAAEVIPTTVRGRGLGLIMALGALGGLSGPAQRLHMG-----HGAFLQHVVLAACALLCILSIML 603

  Fly   498 LPETRNKKLPMSLAEGE 514
            ||||:.|.||..|.:||
Human   604 LPETKRKLLPEVLRDGE 620

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	145/583 (25%)
		MFS	127..499	CDD:119392	112/435 (26%)
SLC22A17	NP_065105.3	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165153308
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.030