DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG14855 and CG7084

DIOPT Version :9

Sequence 1:	NP_650390.2	Gene:	CG14855 / 41789	FlyBaseID:	FBgn0038260	Length:	556	Species:	Drosophila melanogaster
Sequence 2:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster

Alignment Length:	570	Identity:	152/570 - (26%)
Similarity:	248/570 - (43%)	Gaps:	86/570 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 FEEILAKCGNSSRYQ----FVL---LALYG---YLMVVVSMHYFSQNVISFVPDHWCYHEQLENR 57
            |:.::.|.||..|||    ||.   ||..|   |:.::::::         :|||||.....||.
  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALN---------IPDHWCTVPGRENT 89

  Fly    58 SFAEIE---------------KIYSQFEKPSCTRLEKIDEDGQNHTLSR--ERC-NRWIYKYDFG 104
            :|:..|               |.:|..|.......|..|....|..|::  |.| |.|.|...:.
  Fly    90 NFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKTTEACQNGWSYDKTWY 154

  Fly   105 YKSMNTELNWVCDEAYKARVGQSLFFVG---SVCGTLAFGLLGDRIG-RIRALILANWC--GFLG 163
            ..::.|:.||||   .|.....::|.||   .|.|:...|.:||..| |....|...:|  |.||
  Fly   155 ESTIPTDHNWVC---AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLG 216

  Fly   164 DFSTIFAGSLTSFSISRFISGLAADANSYLMYILILEYVSPSLRNVGL-------NTVLGSFYCL 221
              |.:...|.|.|.|...|.||.  .||.        :.||.:  :|:       .:.:..|...
  Fly   217 --SIMCTSSYTWFLIMSGIVGLT--VNSL--------FQSPQI--IGMEISREEDRSRIAFFQSC 267

  Fly   222 G-LIGACWLAV---WVGHWRIFLACSSVPLLLVTLFYFLVQESAQWLVTRNDVDGAIRRLERVAK 282
            | .||...:.:   |:.||..|:..:|:|..:|.||...|.||.:||:::.....||.:|:::||
  Fly   268 GWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAK 332

  Fly   283 IN--RRQVADKDFKDFRIYCEQHYRKDKNQEEHAKLLDMLKTPRMRSTAFKLLLIFIIIVPCYNT 345
            ||  |..:.:|:..:.       |.:|| |:....:..:....|:......:...:.::...|.|
  Fly   333 INGHRFDMTEKELAEI-------YSRDK-QDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFT 389

  Fly   346 IARNVEGLGISPFIMFSLNALTLPPSGYLQGLLQDRMGRKAT-AVGWMAITGIFAVAAGLVISQG 409
            :......:..:||:.|...::...|:..:...:.|..||:.| :|.::.   .|.....:::...
  Fly   390 LVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLI---SFVTCLPIIVYST 451

  Fly   410 SNRNVLLLVGLTMAARFGVSIADGASSQFSTELIPTSVRGRGVAVVHVAGFAASFLSPYILHLGT 474
            ..|...|::.|....:|..::.....:....|:.||.:|..|||:..:...|...|:||:::|||
  Fly   452 DERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGT 516

  Fly   475 YYK-PAPSIILGLLFLSGAYVCLLLPETRNKKLPMSLAEGEEFGRGEGIF 523
            ... .||..|||:|||.|....|.||||.:||||.::.|...||:.:..|
  Fly   517 TVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFF 566

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG14855	NP_650390.2	2A0119	11..507	CDD:273328	144/544 (26%)
CG14855	NP_650390.2	MFS	127..499	CDD:119392	100/392 (26%)
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	136/524 (26%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	97/382 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	100	1.000	Domainoid score	I351
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	97	1.000	Inparanoid score	I321
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
	5	5.060